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dc.contributor.authorHayward, W.
dc.contributor.authorHaseler, Luke
dc.contributor.authorKettwich, L.
dc.contributor.authorichael, A.
dc.contributor.authorSibbitt Jr, W.
dc.contributor.authorBankhurst, A.
dc.date.accessioned2017-05-03T13:12:15Z
dc.date.available2017-05-03T13:12:15Z
dc.date.issued2011
dc.identifier.issn03009742
dc.identifier.doi10.3109/03009742.2011.560892
dc.identifier.urihttp://hdl.handle.net/10072/43497
dc.description.abstractObjective: Hydrodissection and high-pressure injection are important for the treatment of dense connective tissue lesions including rheumatoid nodules, Dupuytren's contracture, and trigger finger. The present study determined the optimal syringes for high-pressure injection of dense connective tissue lesions. Methods: Different sizes (1, 3, 5, 10, 20, and 60 mL) of a mechanical syringe (reciprocating procedure device) with a luerlock fitting were studied. Twenty operators generated maximum pressure with each mechanical syringe size, and pressure was measured in pounds per square inch (psi). Subsequently, 223 dense connective tissue lesions were injected with different sizes of syringes (1, 3, or 10 mL). Outcomes included (i) successful intralesional injection and (ii) clinical response at 2 weeks. Results: Smaller syringes generated significantly more injection pressure than did larger syringes: 1 mL (363 197 psi), 3 mL (177 96 psi), 5 mL (73 40 psi), 10 mL (53 29 psi), 20 mL (32 18 psi), and 60 mL (19 12 psi). Similarly, smaller syringes were superior to larger syringes for intralesional injection success: 10 mL: 34% (15/44) vs. 1 mL: 100% (70/70) (p < 0.001) and 3 mL: 91% (99/109) (p < 0.001). Conclusion: Smaller syringes ( 3 mL) are superior to larger syringes ( 5 mL) for successful hydrodissection and highpressure intralesional injection of dense connective tissue lesions.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherInforma Healthcare
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom379
dc.relation.ispartofpageto382
dc.relation.ispartofissue5
dc.relation.ispartofjournalScandinavian Journal of Rheumatology
dc.relation.ispartofvolume40
dc.rights.retentionY
dc.subject.fieldofresearchCardiovascular medicine and haematology not elsewhere classified
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode320199
dc.subject.fieldofresearchcode3202
dc.titlePressure generated by syringes: implications for hydrodissection and injection of dense connective tissue lesions
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2015-05-31T22:18:06Z
gro.hasfulltextNo Full Text
gro.griffith.authorHaseler, Luke J.


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