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  • Mucosal Fluids and Biomarkers of Clinical Disease: Workshop 3B

    Author(s)
    Johnson, NW
    Malamud, D
    Reznik, D
    Speicher, DJ
    Phelan, J
    Griffith University Author(s)
    Speicher, David J.
    Johnson, Newell W.
    Year published
    2011
    Metadata
    Show full item record
    Abstract
    Diagnostic tests for a range of oral and systemic diseases using fluids sampled from the mouth are under intense investigation and are increasingly being used. Methods exist for identification of HIV antibody and nucleic acid and for other viral infections of the mouth, such as Kaposi sarcoma herpes virus or human herpesvirus-8, which may coexist with HIV. A number of commercial test kits are available, with variable evidence of sensitivity, specificity, and utility. There is intense research on sophisticated but potentially facile handheld in-office devices for many disease markers. Challenges to their uptake require ...
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    Diagnostic tests for a range of oral and systemic diseases using fluids sampled from the mouth are under intense investigation and are increasingly being used. Methods exist for identification of HIV antibody and nucleic acid and for other viral infections of the mouth, such as Kaposi sarcoma herpes virus or human herpesvirus-8, which may coexist with HIV. A number of commercial test kits are available, with variable evidence of sensitivity, specificity, and utility. There is intense research on sophisticated but potentially facile handheld in-office devices for many disease markers. Challenges to their uptake require well-designed studies on their practical reliability and utility, with appropriate controls. A range of ethical, social, and political issues need to be addressed in such studies.
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    Journal Title
    Advances in Dental Research
    Volume
    23
    Issue
    1
    DOI
    https://doi.org/10.1177/0022034511400078
    Subject
    Oral Medicine and Pathology
    Medical Virology
    Clinical Chemistry (diagnostics)
    Dentistry
    Publication URI
    http://hdl.handle.net/10072/43503
    Collection
    • Journal articles

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