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dc.contributor.authorBarnes, Emma C
dc.contributor.authorCarroll, Anthony R
dc.contributor.authorDavis, Rohan A
dc.date.accessioned2021-07-27T00:00:02Z
dc.date.available2021-07-27T00:00:02Z
dc.date.issued2011
dc.date.modified2012-03-29T05:09:28Z
dc.identifier.issn0163-3864
dc.identifier.doi10.1021/np2003676
dc.identifier.urihttp://hdl.handle.net/10072/44090
dc.description.abstractChemical investigations of the Australian plant Eremophila mitchellii resulted in the isolation of the novel tetracyclic sesquiterpene lactones mitchellenes A–C (1–3), the new sesquiterpene acids mitchellenes D and E (4 and 5), and the previously reported natural products 14-hydroxy-6,12-muuroloadien-15-oic acid (6), casticin, and centaureidin. The chemical structures of all compounds were determined by extensive 1D/2D NMR and MS data analysis. Mitchellenes A–C are the first tetracyclic sesquiterpene lactones to be reported; a biosynthetic pathway is proposed for these unique secondary metabolites.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherAmerican Chemical Society
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1888
dc.relation.ispartofpageto1893
dc.relation.ispartofissue9
dc.relation.ispartofjournalJournal of Natural Products
dc.relation.ispartofvolume74
dc.rights.retentionY
dc.subject.fieldofresearchChemical sciences
dc.subject.fieldofresearchBiologically active molecules
dc.subject.fieldofresearchBiological sciences
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchcode34
dc.subject.fieldofresearchcode340401
dc.subject.fieldofresearchcode31
dc.subject.fieldofresearchcode32
dc.titleMitchellenes A-E, Cyclic Sesquiterpenes from the Australian Plant Eremophila mitchellii
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dc.description.versionAccepted Manuscript (AM)
gro.facultyGriffith Sciences, School of Natural Sciences
gro.rights.copyrightThis document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Natural Products, copyright 2011 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/np2003676
gro.date.issued2011
gro.hasfulltextFull Text
gro.griffith.authorDavis, Rohan A.
gro.griffith.authorCarroll, Anthony R.
gro.griffith.authorBarnes, Emma C.


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