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dc.contributor.authorLi, Qin
dc.contributor.authorOhulchanskyy, Tymish Y
dc.contributor.authorLiu, Ruili
dc.contributor.authorKoynov, Kaloian
dc.contributor.authorWu, Dongqing
dc.contributor.authorBest, Andreas
dc.contributor.authorKumar, Rajiv
dc.contributor.authorBonoiu, Adela
dc.contributor.authorPrasad, Paras N
dc.date.accessioned2017-05-03T12:00:08Z
dc.date.available2017-05-03T12:00:08Z
dc.date.issued2010
dc.date.modified2012-04-09T23:26:19Z
dc.identifier.issn1932-7447
dc.identifier.doi10.1021/jp911539r
dc.identifier.urihttp://hdl.handle.net/10072/44331
dc.description.abstractCarbon nanoparticles become photoluminescent upon surface passivation with oligomeric polymer chains. In this work, the dependence of the carbon dots photoluminescent properties on the passivation polymer selection has been demonstrated by conjugating polyethylene glycol (PEG) chains, polyethylenimide-co-polyethylene glycol-co-polyethylenimide copolymer, and 4-armed PEG molecules, respectively. The cytotoxicity and cellular internalization of the resulting three types of photoluminescent nanoformulations of carbon dots, named CD2, CD3, and CD4, were evaluated. These nanoformulations exhibited no apparent cytotoxicity on their own and were shown to successfully target cancer cells by conjugation with transferrin. The implication to the use of carbon dots as biocompatible optical nanoprobes for in vitro cancer diagnostics is discussed.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherAmerican Chemical Society
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom12062
dc.relation.ispartofpageto12068
dc.relation.ispartofjournalThe Journal of Physical Chemistry Part C: Nanomaterials, Interfaces and Hard Matter
dc.relation.ispartofvolume114
dc.rights.retentionY
dc.subject.fieldofresearchChemical sciences
dc.subject.fieldofresearchEngineering
dc.subject.fieldofresearchChemical engineering not elsewhere classified
dc.subject.fieldofresearchcode34
dc.subject.fieldofresearchcode40
dc.subject.fieldofresearchcode400499
dc.titlePhotoluminescent Carbon Dots as Biocompatible Nanoprobes for Targeting Cancer Cells in Vitro
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyrightSelf-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the author[s] for more information.
gro.date.issued2010
gro.hasfulltextNo Full Text
gro.griffith.authorLi, Qin


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