Dihydro-resveratrol—A potent dietary polyphenol

Author(s)
A. Gakh, Andrei
Anisimova, Natalia
V. Kiselevsky, Mikhail
V. Sadovnikov, Sergey
N. Stankov, Ivan
V. Yudin, Mikhail
A. Rufanov, Konstantin
Krasavin, Mikhail
V. Sosnov, Andrey
Griffith University Author(s)
Year published
2010
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Abstract
Dihydro-resveratrol (dihydro-R), a prominent polyphenol component of red wine, has a profound proliferative effect on hormone-sensitive tumor cell lines such as breast cancer cell line MCF7. We found a significant increase in MCF7 tumor cells growth rates in the presence of picomolar concentrations of this compound. The proliferative effect of dihydro-R was not observed in cell lines that do not express hormone receptors (MDA-MB-231, BT-474, and ?-562).
Journal Title
Bioorganic & Medicinal Chemistry Letters
Volume
20
Issue
20
DOI
Subject
Biologically Active Molecules
Medicinal and Biomolecular Chemistry
Organic Chemistry
Pharmacology and Pharmaceutical Sciences
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Collection