• myGriffith
    • Staff portal
    • Contact Us⌄
      • Future student enquiries 1800 677 728
      • Current student enquiries 1800 154 055
      • International enquiries +61 7 3735 6425
      • General enquiries 07 3735 7111
      • Online enquiries
      • Staff phonebook
    View Item 
    •   Home
    • Griffith Research Online
    • Journal articles
    • View Item
    • Home
    • Griffith Research Online
    • Journal articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

  • All of Griffith Research Online
    • Communities & Collections
    • Authors
    • By Issue Date
    • Titles
  • This Collection
    • Authors
    • By Issue Date
    • Titles
  • Statistics

  • Most Popular Items
  • Statistics by Country
  • Most Popular Authors
  • Support

  • Contact us
  • FAQs
  • Admin login

  • Login
  • Association of -592 Region of IL-10 Polymorphisms with Asthma in South-Eastern Iranian Patients

    Thumbnail
    View/Open
    79131_1.pdf (203.5Kb)
    Author(s)
    Hakimizadeh, Elham
    Arababadi, Mohammad Kazemi
    Hassanshahi, Gholamhossein
    Ahmadabadi, Behzad Nasiri
    Hakimi, Hamid
    Rezaeian, Mohsen
    Salehabadi, Vajihe Akbarpour
    Yousefidaredor, Hassan
    Abousaidi, Hamid
    Kennedy, Derek
    Griffith University Author(s)
    Kennedy, Derek D.
    Year published
    2012
    Metadata
    Show full item record
    Abstract
    Background: Cytokines are considered important factors for the pathogenesis of asthma as they play a key role in the regulation of immune responses. The aim of this study was to investigate the association between this disease and polymorphisms in the -592 region of the IL-10 gene. METHODS: This study was carried out on 100 asthmatic patients and 100 healthy controls. PCR-RFLP was applied to examine the polymorphisms in the -592 region of the IL-10 gene. RESULTS: Our results showed a significant difference between patients and controls in terms of genotypes and alleles of the -592 region of the IL-10 gene. CONCLUSIONS: ...
    View more >
    Background: Cytokines are considered important factors for the pathogenesis of asthma as they play a key role in the regulation of immune responses. The aim of this study was to investigate the association between this disease and polymorphisms in the -592 region of the IL-10 gene. METHODS: This study was carried out on 100 asthmatic patients and 100 healthy controls. PCR-RFLP was applied to examine the polymorphisms in the -592 region of the IL-10 gene. RESULTS: Our results showed a significant difference between patients and controls in terms of genotypes and alleles of the -592 region of the IL-10 gene. CONCLUSIONS: According to our results, it can be concluded that the IL-10 promoter polymorphisms may play a crucial role in the pathogenesis of asthma.
    View less >
    Journal Title
    Clinical Laboratory
    Volume
    58
    Issue
    3-4
    Publisher URI
    http://www.clin-lab-publications.com/issue/80
    Copyright Statement
    © 2012 Clinical Laboratory Publications. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
    Subject
    Clinical sciences
    Medical genetics (excl. cancer genetics)
    Publication URI
    http://hdl.handle.net/10072/47602
    Collection
    • Journal articles

    Footer

    Disclaimer

    • Privacy policy
    • Copyright matters
    • CRICOS Provider - 00233E
    • TEQSA: PRV12076

    Tagline

    • Gold Coast
    • Logan
    • Brisbane - Queensland, Australia
    First Peoples of Australia
    • Aboriginal
    • Torres Strait Islander