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dc.contributor.authorSherwin, Justin
dc.contributor.authorMcKnight, Charlotte
dc.contributor.authorHewitt, Alex
dc.contributor.authorGriffiths, Lyn
dc.contributor.authorCoroneo, Minas
dc.contributor.authorMackey, David
dc.date.accessioned2017-05-03T11:39:32Z
dc.date.available2017-05-03T11:39:32Z
dc.date.issued2012
dc.date.modified2013-06-17T03:51:57Z
dc.identifier.issn14682079
dc.identifier.doi10.1136/bjophthalmol-2011-301255
dc.identifier.urihttp://hdl.handle.net/10072/47649
dc.description.abstractBackground Conjunctival ultraviolet autofluorescence (UVAF) photography was developed to detect and characterise pre-clinical sunlight-induced UV damage. The reliability of this measurement and its relationship to outdoor activity are currently unknown. Methods 599 people aged 16e85 years in the crosssectional Norfolk Island Eye Study were included in the validation study. 196 UVAF individual photographs (49 people) and 60 UVAF photographs (15 people) of Norfolk Island Eye Study participants were used for intra- and inter-observer reliability assessment, respectively.Conjunctival UVAF was measured using UV photography. UVAF area was calculated using computerised methods by one grader on two occasions (intra-observer analysis) or two graders (inter-observer analysis). Outdoor activity category, during summer and winter separately, was determined with a UV questionnaire. Total UVAF equalled the area measured in four conjunctival areas (nasal/temporal conjunctiva of right and left eyes). Results Intra-observer (r_c찮988, 95% CI 0.967 to 0.996, p<0.001), and inter-observer concordance correlation coefficients (r_c찮924, 95% CI 0.870 to 0.956, p<0.001) of total UVAF exceeded 0.900. When grouped according to 10 mm2 total UVAF increments, intra- and inter-observer reliability was very good (k찮81) and good (k찮71), respectively. Increasing time outdoors was strongly with increasing total UVAF in summer and winter (ptrend <0.001). Conclusion Intra- and inter-observer reliability of conjunctival UVAF is high. In this population, UVAF correlates strongly with the authors' survey-based assessment of time spent outdoors.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent220737 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherBMJ Publishing Group
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom801
dc.relation.ispartofpageto805
dc.relation.ispartofissue6
dc.relation.ispartofjournalBritish Journal of Opthalmology
dc.relation.ispartofvolume96
dc.rights.retentionY
dc.subject.fieldofresearchMedical and Health Sciences not elsewhere classified
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchOpthalmology and Optometry
dc.subject.fieldofresearchPublic Health and Health Services
dc.subject.fieldofresearchcode119999
dc.subject.fieldofresearchcode1103
dc.subject.fieldofresearchcode1113
dc.subject.fieldofresearchcode1117
dc.titleReliability and validity of conjunctival ultraviolet autofluorescence measurement
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyright© The Author(s) 2012. The attached file is reproduced here in accordance with the copyright policy of the publisher. For information about this journal please refer to the journal’s website or contact the authors.
gro.date.issued2012
gro.hasfulltextFull Text
gro.griffith.authorGriffiths, Lyn


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