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dc.contributor.authorSherwin, Justinen_US
dc.contributor.authorMcKnight, Charlotteen_US
dc.contributor.authorHewitt, Alexen_US
dc.contributor.authorGriffiths, Lynen_US
dc.contributor.authorCoroneo, Minasen_US
dc.contributor.authorMackey, Daviden_US
dc.date.accessioned2017-05-03T11:39:32Z
dc.date.available2017-05-03T11:39:32Z
dc.date.issued2012en_US
dc.date.modified2013-06-17T03:51:57Z
dc.identifier.issn14682079en_US
dc.identifier.doi10.1136/bjophthalmol-2011-301255en_US
dc.identifier.urihttp://hdl.handle.net/10072/47649
dc.description.abstractBackground Conjunctival ultraviolet autofluorescence (UVAF) photography was developed to detect and characterise pre-clinical sunlight-induced UV damage. The reliability of this measurement and its relationship to outdoor activity are currently unknown. Methods 599 people aged 16e85 years in the crosssectional Norfolk Island Eye Study were included in the validation study. 196 UVAF individual photographs (49 people) and 60 UVAF photographs (15 people) of Norfolk Island Eye Study participants were used for intra- and inter-observer reliability assessment, respectively.Conjunctival UVAF was measured using UV photography. UVAF area was calculated using computerised methods by one grader on two occasions (intra-observer analysis) or two graders (inter-observer analysis). Outdoor activity category, during summer and winter separately, was determined with a UV questionnaire. Total UVAF equalled the area measured in four conjunctival areas (nasal/temporal conjunctiva of right and left eyes). Results Intra-observer (r_c찮988, 95% CI 0.967 to 0.996, p<0.001), and inter-observer concordance correlation coefficients (r_c찮924, 95% CI 0.870 to 0.956, p<0.001) of total UVAF exceeded 0.900. When grouped according to 10 mm2 total UVAF increments, intra- and inter-observer reliability was very good (k찮81) and good (k찮71), respectively. Increasing time outdoors was strongly with increasing total UVAF in summer and winter (ptrend <0.001). Conclusion Intra- and inter-observer reliability of conjunctival UVAF is high. In this population, UVAF correlates strongly with the authors' survey-based assessment of time spent outdoors.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.format.extent220737 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglishen_US
dc.language.isoen_US
dc.publisherBMJ Publishing Groupen_US
dc.publisher.placeUnited Kingdomen_US
dc.relation.ispartofstudentpublicationNen_US
dc.relation.ispartofpagefrom801en_US
dc.relation.ispartofpageto805en_US
dc.relation.ispartofissue6en_US
dc.relation.ispartofjournalBritish Journal of Opthalmologyen_US
dc.relation.ispartofvolume96en_US
dc.rights.retentionYen_US
dc.subject.fieldofresearchMedical and Health Sciences not elsewhere classifieden_US
dc.subject.fieldofresearchcode119999en_US
dc.titleReliability and validity of conjunctival ultraviolet autofluorescence measurementen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.rights.copyrightCopyright remains with the authors 2012. The attached file is reproduced here in accordance with the copyright policy of the publisher. For information about this journal please refer to the journal’s website or contact the authors.en_US
gro.date.issued2012
gro.hasfulltextFull Text


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