The characterisation of two halogenated cathinone analogues: 3,5-Difluoromethcathinone and 3,5-dichloromethcathinone
Author(s)
Davis, Sean
Rands-Trevor, Karen
Boyd, Sue
Edirisinghe, Methsiri
Griffith University Author(s)
Year published
2012
Metadata
Show full item recordAbstract
Australia has seen an increase in the importation and use of drugs that are marketed and sold as "Legal Highs". These compounds have largely tended to be various cathinone analogues, with 4-methylmethcathinone the most prominent to date. In January 2009, unknown samples were submitted for analysis along with a large seizure of 3-fluoromethcathinone as part of a police operation. The samples were analysed and determined to be 3,5-difluoromethcathinone and 3,5-dichloromethcathinone. These compounds were synthesised and characterised. The GC-MS data of the samples and their N-acetyl derivatives, NMR, vapour-phase and condensed-phase ...
View more >Australia has seen an increase in the importation and use of drugs that are marketed and sold as "Legal Highs". These compounds have largely tended to be various cathinone analogues, with 4-methylmethcathinone the most prominent to date. In January 2009, unknown samples were submitted for analysis along with a large seizure of 3-fluoromethcathinone as part of a police operation. The samples were analysed and determined to be 3,5-difluoromethcathinone and 3,5-dichloromethcathinone. These compounds were synthesised and characterised. The GC-MS data of the samples and their N-acetyl derivatives, NMR, vapour-phase and condensed-phase IR for these previously unreported compounds are presented. This analytical data will enable laboratories to confirm the presence of these compounds in the absence of commercially available reference standards.
View less >
View more >Australia has seen an increase in the importation and use of drugs that are marketed and sold as "Legal Highs". These compounds have largely tended to be various cathinone analogues, with 4-methylmethcathinone the most prominent to date. In January 2009, unknown samples were submitted for analysis along with a large seizure of 3-fluoromethcathinone as part of a police operation. The samples were analysed and determined to be 3,5-difluoromethcathinone and 3,5-dichloromethcathinone. These compounds were synthesised and characterised. The GC-MS data of the samples and their N-acetyl derivatives, NMR, vapour-phase and condensed-phase IR for these previously unreported compounds are presented. This analytical data will enable laboratories to confirm the presence of these compounds in the absence of commercially available reference standards.
View less >
Journal Title
Forensic Science International
Volume
217
Issue
1-3
Subject
Analytical Spectrometry
Forensic Chemistry