Community-associated methicillin-resistant Staphylococcus aureus endocarditis ‘down under’: Case series and literature review
Author(s)
Townell, Nicola J
Munckhof, Wendy J
Nimmo, Graeme
Bannan, Aiveen
Holley, Anthony
Daniel, Abhay
Bennett, Cameron
Coulter, Christopher
Looke, David FM
Griffith University Author(s)
Year published
2012
Metadata
Show full item recordAbstract
Infective endocarditis is a common complication of Staphylococcus aureus bacteraemia, but literature reports of community- associated methicillin-resistant S. aureus (CA-MRSA) endocarditis are relatively uncommon and mostly comprise intravenous drug users (IVDUs) with the USA300 strain. We report 5 cases of CA-MRSA endocarditis in previously healthy young Australian adults, 4 in IVDUs. Morbidity was high with frequent septic emboli; 3 patients required cardiac surgery and 1 patient died. Typing revealed the 2 most common Australian strains, the Panton - Valentine leukocidin (PVL)-positive ST93 (Queensland) strain and ...
View more >Infective endocarditis is a common complication of Staphylococcus aureus bacteraemia, but literature reports of community- associated methicillin-resistant S. aureus (CA-MRSA) endocarditis are relatively uncommon and mostly comprise intravenous drug users (IVDUs) with the USA300 strain. We report 5 cases of CA-MRSA endocarditis in previously healthy young Australian adults, 4 in IVDUs. Morbidity was high with frequent septic emboli; 3 patients required cardiac surgery and 1 patient died. Typing revealed the 2 most common Australian strains, the Panton - Valentine leukocidin (PVL)-positive ST93 (Queensland) strain and the PVL-negative ST1 (WA-MRSA-1) strain.
View less >
View more >Infective endocarditis is a common complication of Staphylococcus aureus bacteraemia, but literature reports of community- associated methicillin-resistant S. aureus (CA-MRSA) endocarditis are relatively uncommon and mostly comprise intravenous drug users (IVDUs) with the USA300 strain. We report 5 cases of CA-MRSA endocarditis in previously healthy young Australian adults, 4 in IVDUs. Morbidity was high with frequent septic emboli; 3 patients required cardiac surgery and 1 patient died. Typing revealed the 2 most common Australian strains, the Panton - Valentine leukocidin (PVL)-positive ST93 (Queensland) strain and the PVL-negative ST1 (WA-MRSA-1) strain.
View less >
Journal Title
Scandinavian Journal of Infectious Diseases
Volume
44
Issue
7
Subject
Medical and Health Sciences not elsewhere classified
Clinical Sciences