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  • Community-associated methicillin-resistant Staphylococcus aureus endocarditis ‘down under’: Case series and literature review

    Author(s)
    Townell, Nicola J
    Munckhof, Wendy J
    Nimmo, Graeme
    Bannan, Aiveen
    Holley, Anthony
    Daniel, Abhay
    Bennett, Cameron
    Coulter, Christopher
    Looke, David FM
    Griffith University Author(s)
    Nimmo, Graeme R.
    Year published
    2012
    Metadata
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    Abstract
    Infective endocarditis is a common complication of Staphylococcus aureus bacteraemia, but literature reports of community- associated methicillin-resistant S. aureus (CA-MRSA) endocarditis are relatively uncommon and mostly comprise intravenous drug users (IVDUs) with the USA300 strain. We report 5 cases of CA-MRSA endocarditis in previously healthy young Australian adults, 4 in IVDUs. Morbidity was high with frequent septic emboli; 3 patients required cardiac surgery and 1 patient died. Typing revealed the 2 most common Australian strains, the Panton - Valentine leukocidin (PVL)-positive ST93 (Queensland) strain and ...
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    Infective endocarditis is a common complication of Staphylococcus aureus bacteraemia, but literature reports of community- associated methicillin-resistant S. aureus (CA-MRSA) endocarditis are relatively uncommon and mostly comprise intravenous drug users (IVDUs) with the USA300 strain. We report 5 cases of CA-MRSA endocarditis in previously healthy young Australian adults, 4 in IVDUs. Morbidity was high with frequent septic emboli; 3 patients required cardiac surgery and 1 patient died. Typing revealed the 2 most common Australian strains, the Panton - Valentine leukocidin (PVL)-positive ST93 (Queensland) strain and the PVL-negative ST1 (WA-MRSA-1) strain.
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    Journal Title
    Scandinavian Journal of Infectious Diseases
    Volume
    44
    Issue
    7
    DOI
    https://doi.org/10.3109/00365548.2012.664779
    Subject
    Medical and Health Sciences not elsewhere classified
    Clinical Sciences
    Publication URI
    http://hdl.handle.net/10072/47718
    Collection
    • Journal articles

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