Suramin: Clinical Uses and Structure-Activity Relationships
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Suramin is a polysulfonated polyaromatic symmetrical urea. It is currently used to treat African river blindness and African sleeping sickness. Suramin has also been extensively trialed recently to treat a number of other diseases, including many cancers. Here, we examine its modes of action and discuss its structure-activity relationships.
Mini-Reviews in Medicinal Chemistry
Medicinal and Biomolecular Chemistry not elsewhere classified