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dc.contributor.authorSankarasubramanian, Sankar
dc.date.accessioned2017-05-03T15:35:36Z
dc.date.available2017-05-03T15:35:36Z
dc.date.issued2012
dc.date.modified2013-06-07T00:12:39Z
dc.identifier.issn00166731
dc.identifier.doi10.1534/genetics.111.137893
dc.identifier.urihttp://hdl.handle.net/10072/48189
dc.description.abstractHere I show a gradual decline in the proportion of deleterious nonsynonymous SNPs (nSNPs) from tip to root of the human population tree. This study reveals that up to 48% of nSNPs speci?c to a single genome are deleterious in nature, which underscores the abundance of deleterious polymorphisms in humans.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherGenetics Society of America
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1579
dc.relation.ispartofpageto1583
dc.relation.ispartofissue4
dc.relation.ispartofjournalGenetics
dc.relation.ispartofvolume190
dc.rights.retentionY
dc.subject.fieldofresearchEvolutionary Biology not elsewhere classified
dc.subject.fieldofresearchGenetics
dc.subject.fieldofresearchcode060399
dc.subject.fieldofresearchcode0604
dc.titleThe Abundance of Deleterious Polymorphisms in Humans
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Sciences, Griffith School of Environment
gro.rights.copyrightSelf-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the authors for more information.
gro.date.issued2012
gro.hasfulltextNo Full Text
gro.griffith.authorSankarasubramanian, Sankar


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