dc.contributor.author | Sankarasubramanian, Sankar | |
dc.date.accessioned | 2017-05-03T15:35:36Z | |
dc.date.available | 2017-05-03T15:35:36Z | |
dc.date.issued | 2012 | |
dc.date.modified | 2013-06-07T00:12:39Z | |
dc.identifier.issn | 00166731 | |
dc.identifier.doi | 10.1534/genetics.111.137893 | |
dc.identifier.uri | http://hdl.handle.net/10072/48189 | |
dc.description.abstract | Here I show a gradual decline in the proportion of deleterious nonsynonymous SNPs (nSNPs) from tip to root of the human population tree. This study reveals that up to 48% of nSNPs speci?c to a single genome are deleterious in nature, which underscores the abundance of deleterious polymorphisms in humans. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Genetics Society of America | |
dc.publisher.place | United States | |
dc.relation.ispartofstudentpublication | N | |
dc.relation.ispartofpagefrom | 1579 | |
dc.relation.ispartofpageto | 1583 | |
dc.relation.ispartofissue | 4 | |
dc.relation.ispartofjournal | Genetics | |
dc.relation.ispartofvolume | 190 | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Evolutionary Biology not elsewhere classified | |
dc.subject.fieldofresearch | Genetics | |
dc.subject.fieldofresearchcode | 060399 | |
dc.subject.fieldofresearchcode | 0604 | |
dc.title | The Abundance of Deleterious Polymorphisms in Humans | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.faculty | Griffith Sciences, Griffith School of Environment | |
gro.rights.copyright | Self-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the authors for more information. | |
gro.date.issued | 2012 | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Sankarasubramanian, Sankar | |