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dc.contributor.authorDevakaram, Ruth
dc.contributor.authorBlack, David StC
dc.contributor.authorChoomuenwai, Vanida
dc.contributor.authorDavis, Rohan A
dc.contributor.authorKumar, Naresh
dc.date.accessioned2017-05-03T12:46:45Z
dc.date.available2017-05-03T12:46:45Z
dc.date.issued2012
dc.date.modified2013-06-17T23:09:20Z
dc.identifier.issn0968-0896
dc.identifier.doi10.1016/j.bmc.2011.12.037
dc.identifier.urihttp://hdl.handle.net/10072/48682
dc.description.abstract5-Methoxyflavenes and 6-methoxyflavenes were found to undergo stereoselective acid-catalyzed rearrangement to generate a range ofnovel chromeno[2,3-b]chromene derivatives. When subjected to an in vitro antiplasmodial growth inhibition assay using Plasmodium falciparum (3D7 line) the chromene analogues were shown to display IC50 values ranging from 6.8 to 39.8 μM.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeNetherlands
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1527
dc.relation.ispartofpageto1534
dc.relation.ispartofissue4
dc.relation.ispartofjournalBioorganic & Medicinal Chemistry
dc.relation.ispartofvolume20
dc.rights.retentionY
dc.subject.fieldofresearchMedicinal and biomolecular chemistry
dc.subject.fieldofresearchBiologically active molecules
dc.subject.fieldofresearchOrganic chemistry
dc.subject.fieldofresearchPharmacology and pharmaceutical sciences
dc.subject.fieldofresearchcode3404
dc.subject.fieldofresearchcode340401
dc.subject.fieldofresearchcode3405
dc.subject.fieldofresearchcode3214
dc.titleSynthesis and antiplasmodial evaluation of novel chromeno[2,3-b]chromene derivatives
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2012
gro.hasfulltextNo Full Text
gro.griffith.authorDavis, Rohan A.


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