dc.contributor.author | Devakaram, Ruth | |
dc.contributor.author | Black, David StC | |
dc.contributor.author | Choomuenwai, Vanida | |
dc.contributor.author | Davis, Rohan A | |
dc.contributor.author | Kumar, Naresh | |
dc.date.accessioned | 2017-05-03T12:46:45Z | |
dc.date.available | 2017-05-03T12:46:45Z | |
dc.date.issued | 2012 | |
dc.date.modified | 2013-06-17T23:09:20Z | |
dc.identifier.issn | 0968-0896 | |
dc.identifier.doi | 10.1016/j.bmc.2011.12.037 | |
dc.identifier.uri | http://hdl.handle.net/10072/48682 | |
dc.description.abstract | 5-Methoxyflavenes and 6-methoxyflavenes were found to undergo stereoselective acid-catalyzed rearrangement to generate a range ofnovel chromeno[2,3-b]chromene derivatives. When subjected to an in vitro antiplasmodial growth inhibition assay using Plasmodium falciparum (3D7 line) the chromene analogues were shown to display IC50 values ranging from 6.8 to 39.8 μM. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.publisher.place | Netherlands | |
dc.relation.ispartofstudentpublication | N | |
dc.relation.ispartofpagefrom | 1527 | |
dc.relation.ispartofpageto | 1534 | |
dc.relation.ispartofissue | 4 | |
dc.relation.ispartofjournal | Bioorganic & Medicinal Chemistry | |
dc.relation.ispartofvolume | 20 | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Medicinal and biomolecular chemistry | |
dc.subject.fieldofresearch | Biologically active molecules | |
dc.subject.fieldofresearch | Organic chemistry | |
dc.subject.fieldofresearch | Pharmacology and pharmaceutical sciences | |
dc.subject.fieldofresearchcode | 3404 | |
dc.subject.fieldofresearchcode | 340401 | |
dc.subject.fieldofresearchcode | 3405 | |
dc.subject.fieldofresearchcode | 3214 | |
dc.title | Synthesis and antiplasmodial evaluation of novel chromeno[2,3-b]chromene derivatives | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.date.issued | 2012 | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Davis, Rohan A. | |