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dc.contributor.authorMoriel, Danilo G
dc.contributor.authorRosini, Roberto
dc.contributor.authorSeib, Kate L
dc.contributor.authorSerino, Laura
dc.contributor.authorPizza, Mariagrazia
dc.contributor.authorRappuoli, Rino
dc.date.accessioned2017-05-03T15:50:53Z
dc.date.available2017-05-03T15:50:53Z
dc.date.issued2012
dc.date.modified2013-06-18T00:07:29Z
dc.identifier.issn2150-7511
dc.identifier.doi10.1128/mBio.00118-12
dc.identifier.urihttp://hdl.handle.net/10072/48715
dc.description.abstractEscherichia coli outbreak in Germany, which resulted in more than 4,000 cases, including 908 cases of hemolytic-uremic syndrome (HUS) and at least 50 deaths, highlighted the genome plasticity of E. coli and the potential for new virulent strains to emerge. The analysis of 170 E. coli genome sequences for the presence of nine previously identified protective extraintestinal pathogenic E. coli antigens suggested the feasibility of a combination vaccine as a universal intervention against all pathogenic E. coli strains. IMPORTANCE: This article reports on the feasibility of a combination vaccine as a universal intervention against all pathogenic Escherichia coli strains.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent4684023 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherAmerican Society for Microbiology
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrome00118-12-1
dc.relation.ispartofpagetoe00118-12-3
dc.relation.ispartofissue3
dc.relation.ispartofjournalmBio
dc.relation.ispartofvolume3
dc.rights.retentionY
dc.subject.fieldofresearchMicrobiology
dc.subject.fieldofresearchMedical bacteriology
dc.subject.fieldofresearchcode3107
dc.subject.fieldofresearchcode320701
dc.titleEscherichia coli: Great Diversity around a Common Core
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyright© 2012 American Society for Microbiology. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.date.issued2012
gro.hasfulltextFull Text
gro.griffith.authorSeib, Kate


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