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dc.contributor.authorShatabda, S
dc.contributor.authorNewton, MAH
dc.contributor.authorPham, DN
dc.contributor.authorSattar, A
dc.contributor.editorSanjay Ranka
dc.date.accessioned2018-03-26T01:31:13Z
dc.date.available2018-03-26T01:31:13Z
dc.date.issued2012
dc.date.modified2014-04-08T23:55:21Z
dc.identifier.isbn9781450316705
dc.identifier.refurihttp://www.cse.buffalo.edu/ACM-BCB2012/
dc.identifier.doi10.1145/2382936.2382980
dc.identifier.urihttp://hdl.handle.net/10072/48902
dc.description.abstractProtein structure prediction is one of the most challenging problems in computational biology. Given a protein's amino acid sequence, a simplified version of the problem is to find an on-lattice self-avoiding walk that minimizes the interaction energy among the amino acids. In this paper, we present a memory-based local search method for the simplified problem using Hydrophobic-Polar energy model and Face Centered Cubic lattice. By memorizing local minima and then avoiding their neighbohood, our approach significantly improves the state-of-the-art local search method for protein structure prediction on a set of standard benchmark proteins.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent1147000 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherACM
dc.publisher.placeUnited States
dc.publisher.urihttp://www.cse.buffalo.edu/ACM-BCB2012/
dc.relation.ispartofstudentpublicationY
dc.relation.ispartofconferencenameACM BCB 2012
dc.relation.ispartofconferencetitle2012 ACM Conference on Bioinformatics, Computational Biology and Biomedicine, BCB 2012
dc.relation.ispartofdatefrom2012-10-07
dc.relation.ispartofdateto2012-10-10
dc.relation.ispartoflocationOrlando, Florida, United States
dc.relation.ispartofpagefrom345
dc.relation.ispartofpageto352
dc.rights.retentionY
dc.subject.fieldofresearchArtificial intelligence not elsewhere classified
dc.subject.fieldofresearchcode460299
dc.titleMemory-Based Local Search for Simplified Protein Structure Prediction
dc.typeConference output
dc.type.descriptionE1 - Conferences
dc.type.codeE - Conference Publications
gro.facultyGriffith Sciences, School of Information and Communication Technology
gro.rights.copyright© ACM, 2012. This is the author's version of the work. It is posted here by permission of ACM for your personal use. Not for redistribution. The definitive version was published in Proceedings of the ACM Conference on Bioinformatics, Computational Biology and Biomedicine , ISBN: 978-1-4503-1670-5, dx.doi.org/10.1145/2382936.2382980
gro.date.issued2012
gro.hasfulltextFull Text
gro.griffith.authorSattar, Abdul


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  • Conference outputs
    Contains papers delivered by Griffith authors at national and international conferences.

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