dc.contributor.author | Magolan, Jakob | |
dc.contributor.author | Adams, Nathan BP | |
dc.contributor.author | Onozuka, Hiroko | |
dc.contributor.author | Hungerford, Natasha L | |
dc.contributor.author | Esumi, Hiroyasu | |
dc.contributor.author | Coster, Mark J | |
dc.date.accessioned | 2017-07-17T12:30:37Z | |
dc.date.available | 2017-07-17T12:30:37Z | |
dc.date.issued | 2012 | |
dc.date.modified | 2013-03-06T01:00:59Z | |
dc.identifier.issn | 1860-7179 | |
dc.identifier.doi | 10.1002/cmdc.201100564 | |
dc.identifier.uri | http://hdl.handle.net/10072/49282 | |
dc.description.abstract | Inspired by nature: Angelmarin is an anticancer natural product with potent antiausterity activity, that is, selective cytotoxicity towards nutrient-deprived, resistant cancer cells. Through structure-activity relationship studies, three analogues were identified as lead compounds for the develpoment of molecular probes for the investigation of the mode of action and biological targets of the antiausterity compounds. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Wiley | |
dc.publisher.place | Germany | |
dc.relation.ispartofstudentpublication | N | |
dc.relation.ispartofpagefrom | 766 | |
dc.relation.ispartofpageto | 770 | |
dc.relation.ispartofissue | 5 | |
dc.relation.ispartofjournal | ChemMedChem | |
dc.relation.ispartofvolume | 7 | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Medicinal and biomolecular chemistry | |
dc.subject.fieldofresearch | Biologically active molecules | |
dc.subject.fieldofresearch | Organic chemistry | |
dc.subject.fieldofresearch | Organic chemical synthesis | |
dc.subject.fieldofresearch | Pharmacology and pharmaceutical sciences | |
dc.subject.fieldofresearchcode | 3404 | |
dc.subject.fieldofresearchcode | 340401 | |
dc.subject.fieldofresearchcode | 3405 | |
dc.subject.fieldofresearchcode | 340503 | |
dc.subject.fieldofresearchcode | 3214 | |
dc.title | Synthesis and Evaluation of Anticancer Natural Product Analogues Based on Angelmarin: Targeting the Tolerance towards Nutrient Deprivation | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.faculty | Griffith Sciences, Griffith Institute for Drug Discovery | |
gro.date.issued | 2012 | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Coster, Mark J. | |
gro.griffith.author | Hungerford, Natasha L. | |
gro.griffith.author | Magolan, Jakob | |
gro.griffith.author | Adams, Nathan | |