A reliable synthesis of 2- and 6-amino-β-cyclodextrin and permethylated-β-cyclodextrin
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A new, reliable method for the introduction of an amine group at positions 2 or 6 of ߭cyclodextrin and permethyl-߭cyclodextrin is described. It involves selective tosylation followed by azide substitution and almost quantitative reduction with triphenylphosphine followed by hydrolysis of the phosphinimine intermediate.
Copyright 2005 Elsevier : Reproduced in accordance with the copyright policy of the publisher : This journal is available online - use hypertext links.