Microwave-accelerated cross-metathesis reactions of N-allyl amino acid substrates.
Abstract
Microwave heating has been utilised for the cross metathesis reaction of N-allyl amino acid substrates to generate olefin homodimers. Remarkable acceleration of the cross metathesis reaction (minutes compared to hours) over conventional reflux heating was observed. In addition, improved reaction yields and similar E/Z ratios for the cross metathesis products were achieved.
Journal Title
Tetrahedron Letters
Volume
46
Publisher URI
Copyright Statement
© 2005 Elsevier : Reproduced in accordance with the copyright policy of the publisher : This journal is available online - use hypertext links.
Subject
Medicinal and biomolecular chemistry
Organic chemistry