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dc.contributor.authorAssar, Shokrollah
dc.contributor.authorArababadi, Mohammad Kazemi
dc.contributor.authorAhmadabadi, Behzad Nasiri
dc.contributor.authorSalehi, Mansoor
dc.contributor.authorKennedy, Derek
dc.date.accessioned2017-05-03T11:12:37Z
dc.date.available2017-05-03T11:12:37Z
dc.date.issued2012
dc.date.modified2014-08-13T23:53:24Z
dc.identifier.issn1433-6510
dc.identifier.doi10.7754/Clin.Lab.2012.120119
dc.identifier.urihttp://hdl.handle.net/10072/49831
dc.description.abstractHepatitis B virus (HBV) is a serious risk as a disease that can be spread through blood transfusion. Occult hepatitis B infection (OBI) is defined in a patient with the presence of HBV-DNA but a lack of HBsAg in the serum and hepatocytes. OBI can be considered as a high potential risk factor for inducing post transfusion hepatitis (PTH), hepatocellular carcinoma (HCC), cirrhosis, and reactivation of the HBV. Recently, several investigations from various regions of the world have reported PTH as well as HCC and cirrhosis among blood recipients with diseases such as thalassemia and other disorders requiring regular hemodialysis. This form of hepatitis also causes complications for individuals that are co-infected with other viruses such as HCV and HIV. Because of its extreme disease potential, OBI can be considered a high risk for PTH, HCC, and cirrhosis. Therefore, an understanding of the prevalence of OBI among blood donors is a critical strategy in most transfusion services. This review addresses the recent information regarding the prevalence of OBI worldwide, with an additional focus on Iranian blood donors.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent181743 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoen_US
dc.publisherClinical Laboratory Publications
dc.publisher.placeGermany
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1225
dc.relation.ispartofpageto1230
dc.relation.ispartofissue11-12
dc.relation.ispartofjournalClinical Laboratory
dc.relation.ispartofvolume58
dc.rights.retentionY
dc.subject.fieldofresearchInfectious Diseases
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchcode110309
dc.subject.fieldofresearchcode1103
dc.titleOccult Hepatitis B Virus (HBV) Infection: a Global Challenge for Medicine
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyright© 2012 Clinical Laboratory Publications. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.date.issued2012
gro.hasfulltextFull Text
gro.griffith.authorKennedy, Derek D.


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