dc.contributor.author | Young, Megan K | |
dc.contributor.author | Ng, Shu-Kay | |
dc.contributor.author | Mellick, George | |
dc.contributor.author | Scuffham, Paul A | |
dc.date.accessioned | 2017-05-03T14:10:40Z | |
dc.date.available | 2017-05-03T14:10:40Z | |
dc.date.issued | 2013 | |
dc.date.modified | 2014-08-28T22:59:46Z | |
dc.identifier.issn | 0962-9343 | |
dc.identifier.doi | 10.1007/s11136-012-0231-6 | |
dc.identifier.uri | http://hdl.handle.net/10072/49853 | |
dc.description.abstract | Purpose The EuroQoL (EQ-5D) is ideal to compare quality of life across conditions. However, the Parkinson's Disease Questionnaire (PDQ-39) is often the only qualityof- life instrument used in Parkinson's disease research. We aimed to identify associations between PDQ-39 domains and EQ-5D domains, and compare different methods of developing a function to map the PDQ-39 to EQ-5D scores. Methods Adults with Parkinson's disease self-completed both instruments. Ordinal regression identified associations between PDQ-39 domain scores and each EQ-5D domain. Modeling (n = 80) and validation sets (n = 16) were randomly generated. Overall performance of four methods of mapping the PDQ-39 to EQ-5D scores (using PDQ-39 domains and total score in ordinal and linear regression) was assessed with the validation set, followed by assessing the equivalence of observed and predicted EQ-5D scores on the full dataset controlling for sociodemographic factors. Results Different sets of PDQ-39 domains were associated with each EQ-5D domain. For example, PDQ-39 ''Activities of Daily Living'' and ''Social Support'' were associated with EQ-5D ''Personal Care,'' while PDQ-39 ''Emotional Well-being'' was associated with EQ-5D ''Anxiety/Depression.'' Over one-third (37.5 %) of predictions from ordinal regressions had an error /0.01 % (compared to 6.3 % for linear regressions). The EQ-5D scores predicted with ordinal regression using PDQ-39 domains were similar in distribution and association with sociodemographic factors to the observed EQ-5D scores. Conclusions Of the four methods tested, using PDQ-39 domains in ordinal regression was superior for mapping EQ-5D scores. The function reported here may prove particularly useful for cost-utility analyses comparing Parkinson's disease with other conditions. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Springer | |
dc.publisher.place | Netherlands | |
dc.relation.ispartofstudentpublication | N | |
dc.relation.ispartofpagefrom | 1065 | |
dc.relation.ispartofpageto | 1072 | |
dc.relation.ispartofissue | 5 | |
dc.relation.ispartofjournal | Quality of Life Research | |
dc.relation.ispartofvolume | 22 | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Neurology and neuromuscular diseases | |
dc.subject.fieldofresearch | Health sciences | |
dc.subject.fieldofresearch | Human society | |
dc.subject.fieldofresearchcode | 320905 | |
dc.subject.fieldofresearchcode | 42 | |
dc.subject.fieldofresearchcode | 44 | |
dc.title | Mapping of the PDQ-39 to EQ-5D scores in patients with Parkinson’s disease | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.faculty | Griffith Health, School of Medicine | |
gro.date.issued | 2013 | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Mellick, George | |
gro.griffith.author | Scuffham, Paul A. | |
gro.griffith.author | Ng, Shu Kay Angus | |