(Z,Z)-3,6-Bis[(3,4,5-trimethoxyphenyl)-methylene]piperazine-2,5-dione

Loughlin, Wendy; Marshall, Raymond; Fairfull-Smith, Kathryn; Healy, Peter

doi:10.1107/S1600536805012316

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Author

Loughlin, Wendy

Marshall, Raymond

Fairfull-Smith, Kathryn

Healy, Peter

Year published

2005

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Abstract

The title compound, C24H26N2O8, is a derivative of neihumicin, a cytotoxic antibiotic from Micromonospora neihuensis. The compound crystallizes as discrete molecules with crystallographic inversion symmetry. Intermolecular N-HO hydrogen bonds yield polymeric chains along the c axis. The trimethoxyphenylmethylene side chain is found to be in a Z configuration about the C=C double bond.The title compound, C24H26N2O8, is a derivative of neihumicin, a cytotoxic antibiotic from Micromonospora neihuensis. The compound crystallizes as discrete molecules with crystallographic inversion symmetry. Intermolecular N-HO hydrogen bonds yield polymeric chains along the c axis. The trimethoxyphenylmethylene side chain is found to be in a Z configuration about the C=C double bond.
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Journal Title

Acta crystallographica. Section E, Structure reports online

Volume

E61

Issue

Publisher URI

http://journals.iucr.org/e/journalhomepage.html

DOI

https://doi.org/10.1107/S1600536805012316

Copyright Statement

© The Author(s) 2005. For information about this journal please refer to the journal's website. All articles published in Acta Crystallographica Section E are open access and distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. See http://creativecommons.org/licenses/by/2.0/uk/legalcode

Publication URI

http://hdl.handle.net/10072/4998

Collection

Journal articles