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dc.contributor.authorMann0988223, MarettaDNUen_US
dc.contributor.authorThomson, Robinen_US
dc.contributor.authorvon Itzstein, Marken_US
dc.contributor.editorDr D L Bogeren_US
dc.date.accessioned2017-05-03T11:05:38Z
dc.date.available2017-05-03T11:05:38Z
dc.date.issued2004en_US
dc.date.modified2009-10-19T05:23:51Z
dc.identifier.issn0960894Xen_US
dc.identifier.doi10.1016/j.bmcl.2004.08.064en_AU
dc.identifier.urihttp://hdl.handle.net/10072/5049
dc.description.abstractA novel approach to the synthesis of ߭glycosides of N-acetyl-D-glucosaminuronic acid, in six steps and good overall yield from N-acetyl-D-glucosamine, has been developed. The key synthetic step was the Lewis acid mediated O-glycosidation of methyl 1,3,4-tri-O-pivaloyl-N-acetyl-D-glucosaminuronate (11). Elaboration of glucosaminuronides 15 and 18 provided novel sialylmimetics 21 and 22, which showed inhibition of Vibrio cholerae sialidase.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherPergamonen_US
dc.publisher.placeUKen_US
dc.publisher.urihttp://www.elsevier.com/wps/find/journaldescription.cws_home/972/description#descriptionen_AU
dc.relation.ispartofpagefrom5555en_US
dc.relation.ispartofpageto5558en_US
dc.relation.ispartofjournalBiorganic & Medicinal Chemistry Lettersen_US
dc.relation.ispartofvolume14en_US
dc.subject.fieldofresearchcode250302en_US
dc.titleAn efficient approach to N-acetyl-D-glucosaminuronic acid-based sialylmimetics as potential sialidase inhibitorsen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2004
gro.hasfulltextNo Full Text


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