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dc.contributor.authorNevalainen, TJ
dc.contributor.authorQuinn, RJ
dc.contributor.authorHooper, JNA
dc.date.accessioned2017-05-03T13:17:54Z
dc.date.available2017-05-03T13:17:54Z
dc.date.issued2004
dc.date.modified2013-04-29T02:13:32Z
dc.identifier.issn1096-4959
dc.identifier.doi10.1016/j.cbpc.2004.01.010
dc.identifier.urihttp://hdl.handle.net/10072/5054
dc.description.abstractPhospholipase A2 (PLA2) catalytic activity was measured in aqueous extracts of 83 freeze-dried specimens representing 55 marine sponge species collected from the east coast of Australia including the Great Barrier Reef. High levels (>500 u/l) of PLA2 activity (defined as the amount of activity that releases 1 孯l of fatty acid per min) were found in four out of 55 species (7%), moderate activities (100-499 u/l) in 6/55 (11%), low activities (1-99 u/l) in 11/55 (20%) and no PLA2 activity in 34/55 (62%). Species with high PLA2 activity levels included Cymbastela coralliophila (2118 u/l, specific activity 10 590 u/g of protein), Acanthella cavernosa (1318 u/l, specific activity 2470 u/g), Spirastrella vagabunda (1036 u/l, specific activity 1727 u/g and Theonella swinhoei (567 u/l, specific activity 354 u/g). It was postulated that poriferan PLA2 may be involved in eicosanoid metabolism and antimicrobial and toxic defence of the animal.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier Science
dc.publisher.placeNew York
dc.publisher.urihttp://www.elsevier.com/wps/find/journaldescription.cws_home/525465/description#description
dc.relation.ispartofpagefrom413
dc.relation.ispartofpageto420
dc.relation.ispartofjournalComparative Biochemistry and Physiology Part B
dc.relation.ispartofvolume137
dc.subject.fieldofresearchBiochemistry and cell biology
dc.subject.fieldofresearchZoology
dc.subject.fieldofresearchHistory, heritage and archaeology
dc.subject.fieldofresearchcode3101
dc.subject.fieldofresearchcode3109
dc.subject.fieldofresearchcode43
dc.titlePhospholipase A2 in porifera
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2004
gro.hasfulltextNo Full Text
gro.griffith.authorQuinn, Ronald J.
gro.griffith.authorHooper, John N.


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