Chemical Synthesis of the Englerins
Author(s)
Pouwer, Rebecca
Richard, Jean-Alexandre
Tseng, Chih-Chung
Y.-K. Chen, David
Griffith University Author(s)
Year published
2012
Metadata
Show full item recordAbstract
n the long lasting battle against cancer, Nature sometimes gives a helping hand to researchers to find new drugs for the treatment of diseases and improvement of patients' well-being. Englerin A has emerged as a promising anticancer candidate as well as being an exciting synthetic challenge for organic chemists. This focus review summarizes the total syntheses reported to date and the synthetic approaches toward analogues of this fascinating natural product.n the long lasting battle against cancer, Nature sometimes gives a helping hand to researchers to find new drugs for the treatment of diseases and improvement of patients' well-being. Englerin A has emerged as a promising anticancer candidate as well as being an exciting synthetic challenge for organic chemists. This focus review summarizes the total syntheses reported to date and the synthetic approaches toward analogues of this fascinating natural product.
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Journal Title
Chemistry – An Asian Journal
Volume
7
Issue
1
Subject
Organic Chemical Synthesis
Chemical Sciences