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dc.contributor.authorDung, Tri Phung
dc.contributor.authorConnell, Des
dc.contributor.authorMiller, Greg
dc.contributor.authorChu, Cordia
dc.date.accessioned2017-05-03T13:17:05Z
dc.date.available2017-05-03T13:17:05Z
dc.date.issued2012
dc.date.modified2013-06-04T00:24:44Z
dc.identifier.issn1559-0631
dc.identifier.doi10.1038/jes.2012.32
dc.identifier.urihttp://hdl.handle.net/10072/51125
dc.description.abstractChlorpyrifos is the most common organophosphate compound registered for agricultural use in Vietnam. The aim of this study was to evaluate chlorpyrifos exposure to rice farmers in Vietnam, using a probabilistic approach. Urine samples on a 24-h basis were collected from farmers before and post application of pesticide. Samples were analysed for 3,5,6-trichloro-2-pyridinol (TCP), the major urinary metabolite of chlorpyrifos, using an enzymatic pre-treatment for extraction and HPLC-MS/MS. Absorbed daily doses (ADD) of chlorpyrifos for farmers were subsequently estimated from the urinary TCP levels. The baseline and post-application exposure levels were evaluated at the 5th, 50th, and 95th percentile representing low, medium and high-exposure groups in the population. Regression analysis was applied to examine the association between exposure level and factors. The baseline exposure level, which ranged from 0.03 to 1.98?姯kg/day was below the chronic guidelines recommended by international and national bodies. However, the post-application exposure level, which ranged from 0.35 to 94?姯kg/day exceeded most of the acute guidelines at the 95th percentile level. Multivariate analysis provided strong evidence for a relationship between post-application exposure level and amount of chlorpyrifos used, as well as body coverage of personal protective equipment.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherNature Publishing Group
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom417
dc.relation.ispartofpageto423
dc.relation.ispartofissue4
dc.relation.ispartofjournalJournal of Exposure Science and Environmental Epidemiology
dc.relation.ispartofvolume22
dc.rights.retentionY
dc.subject.fieldofresearchChemical sciences
dc.subject.fieldofresearchEnvironmental sciences
dc.subject.fieldofresearchEcology not elsewhere classified
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchEpidemiology
dc.subject.fieldofresearchPublic health
dc.subject.fieldofresearchcode34
dc.subject.fieldofresearchcode41
dc.subject.fieldofresearchcode310399
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode4202
dc.subject.fieldofresearchcode4206
dc.titleProbabilistic assessment of chlorpyrifos exposure to rice farmers in Vietnam
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Sciences, Griffith School of Environment
gro.date.issued2012
gro.hasfulltextNo Full Text
gro.griffith.authorConnell, Des W.
gro.griffith.authorChu, Cordia M.
gro.griffith.authorPhung, Dung T.


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