dc.contributor.author | Dung, Tri Phung | |
dc.contributor.author | Connell, Des | |
dc.contributor.author | Miller, Greg | |
dc.contributor.author | Chu, Cordia | |
dc.date.accessioned | 2017-05-03T13:17:05Z | |
dc.date.available | 2017-05-03T13:17:05Z | |
dc.date.issued | 2012 | |
dc.date.modified | 2013-06-04T00:24:44Z | |
dc.identifier.issn | 1559-0631 | |
dc.identifier.doi | 10.1038/jes.2012.32 | |
dc.identifier.uri | http://hdl.handle.net/10072/51125 | |
dc.description.abstract | Chlorpyrifos is the most common organophosphate compound registered for agricultural use in Vietnam. The aim of this study was to evaluate chlorpyrifos exposure to rice farmers in Vietnam, using a probabilistic approach. Urine samples on a 24-h basis were collected from farmers before and post application of pesticide. Samples were analysed for 3,5,6-trichloro-2-pyridinol (TCP), the major urinary metabolite of chlorpyrifos, using an enzymatic pre-treatment for extraction and HPLC-MS/MS. Absorbed daily doses (ADD) of chlorpyrifos for farmers were subsequently estimated from the urinary TCP levels. The baseline and post-application exposure levels were evaluated at the 5th, 50th, and 95th percentile representing low, medium and high-exposure groups in the population. Regression analysis was applied to examine the association between exposure level and factors. The baseline exposure level, which ranged from 0.03 to 1.98?姯kg/day was below the chronic guidelines recommended by international and national bodies. However, the post-application exposure level, which ranged from 0.35 to 94?姯kg/day exceeded most of the acute guidelines at the 95th percentile level. Multivariate analysis provided strong evidence for a relationship between post-application exposure level and amount of chlorpyrifos used, as well as body coverage of personal protective equipment. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Nature Publishing Group | |
dc.publisher.place | United Kingdom | |
dc.relation.ispartofstudentpublication | N | |
dc.relation.ispartofpagefrom | 417 | |
dc.relation.ispartofpageto | 423 | |
dc.relation.ispartofissue | 4 | |
dc.relation.ispartofjournal | Journal of Exposure Science and Environmental Epidemiology | |
dc.relation.ispartofvolume | 22 | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Chemical sciences | |
dc.subject.fieldofresearch | Environmental sciences | |
dc.subject.fieldofresearch | Ecology not elsewhere classified | |
dc.subject.fieldofresearch | Biomedical and clinical sciences | |
dc.subject.fieldofresearch | Epidemiology | |
dc.subject.fieldofresearch | Public health | |
dc.subject.fieldofresearchcode | 34 | |
dc.subject.fieldofresearchcode | 41 | |
dc.subject.fieldofresearchcode | 310399 | |
dc.subject.fieldofresearchcode | 32 | |
dc.subject.fieldofresearchcode | 4202 | |
dc.subject.fieldofresearchcode | 4206 | |
dc.title | Probabilistic assessment of chlorpyrifos exposure to rice farmers in Vietnam | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.faculty | Griffith Sciences, Griffith School of Environment | |
gro.date.issued | 2012 | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Connell, Des W. | |
gro.griffith.author | Chu, Cordia M. | |
gro.griffith.author | Phung, Dung T. | |