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dc.contributor.authorMcCartan, C
dc.contributor.authorMason, R
dc.contributor.authorJayasinghe, SR
dc.contributor.authorGriffiths, LR
dc.date.accessioned2017-05-03T11:39:35Z
dc.date.available2017-05-03T11:39:35Z
dc.date.issued2012
dc.date.modified2013-06-11T04:44:18Z
dc.identifier.issn2090-2247
dc.identifier.doi10.1155/2012/796926
dc.identifier.urihttp://hdl.handle.net/10072/51402
dc.description.abstractCardiomyopathies represent a group of diseases of the myocardium of the heart and include diseases both primarily of the cardiac muscle and systemic diseases leading to adverse effects on the heart muscle size, shape, and function. Traditionally cardiomyopathies were defined according to phenotypical appearance. Now, as our understanding of the pathophysiology of the different entities classified under each of the different phenotypes improves and our knowledge of the molecular and genetic basis for these entities progresses, the traditional classifications seem oversimplistic and do not reflect current understanding of this myriad of diseases and disease processes. Although our knowledge of the exact basis of many of the disease processes of cardiomyopathies is still in its infancy, it is important to have a classification system that has the ability to incorporate the coming tide of molecular and genetic information. This paper discusses how the traditional classification of cardiomyopathies based on morphology has evolved due to rapid advances in our understanding of the genetic and molecular basis for many of these clinical entities.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent547601 bytes
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.publisherHindawi Publishing Corporation
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom796926-1
dc.relation.ispartofpageto796926-10
dc.relation.ispartofissue796926
dc.relation.ispartofjournalBiochemistry Research International
dc.relation.ispartofvolume2012
dc.rights.retentionY
dc.subject.fieldofresearchMedical and Health Sciences not elsewhere classified
dc.subject.fieldofresearchGenetics
dc.subject.fieldofresearchMedical Biotechnology
dc.subject.fieldofresearchcode119999
dc.subject.fieldofresearchcode0604
dc.subject.fieldofresearchcode1004
dc.titleCardiomyopathy Classification: Ongoing Debate in the Genomics Era
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by-nc-sa/2.1/au/
gro.facultyGriffith Health, School of Medical Science
gro.rights.copyright© The Author(s) 2012. The attached file is posted here with permission of the copyright owners for your personal use only. No further distribution permitted.For information about this journal please refer to the journal’s website. The online version of this work is licensed under a Creative Commons License, available at http://creativecommons.org/licenses/by-nc-sa/2.1/au/
gro.date.issued2012
gro.hasfulltextFull Text
gro.griffith.authorGriffiths, Lyn
gro.griffith.authorMcCartan, Charles
gro.griffith.authorJayasinghe, Satyajit R.


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