Show simple item record

dc.contributor.authorSandulenko, Y.
dc.contributor.authorKrasavin, Mikhail
dc.date.accessioned2017-05-03T15:58:30Z
dc.date.available2017-05-03T15:58:30Z
dc.date.issued2012
dc.date.modified2013-06-20T04:07:52Z
dc.identifier.issn00093122
dc.identifier.doi10.1007/s10593-012-1033-z
dc.identifier.urihttp://hdl.handle.net/10072/51699
dc.description.abstractAnabasine served as a starting material for the synthesis of two series of novel, drug-like compounds. On the one hand, anabasine was subjected to a direct Chichibabin amination and elaborated into medicinally relevant, racemic 6-(piperidin-2-yl)imidazo[1,2-a]pyridines via the Groebke-Blackburn reaction. On the other hand, anabasine was used as an amine for the Ugi reaction to provide novel non-racemic anabasine-containing 2-[(2-pyridin-3-yl)piperidin-1-yl]acetamide peptidomimetics with high diastereoselectivity.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom606
dc.relation.ispartofpageto612
dc.relation.ispartofissue4
dc.relation.ispartofjournalChemistry of Heterocyclic Ccompounds
dc.relation.ispartofvolume48
dc.rights.retentionY
dc.subject.fieldofresearchMedicinal and Biomolecular Chemistry not elsewhere classified
dc.subject.fieldofresearchOrganic Chemistry
dc.subject.fieldofresearchcode030499
dc.subject.fieldofresearchcode0305
dc.titleNatural Products as Templates for Bioactive Compound Libraries. 3. Novel Heterocycles and Peptidomimetics Generated from Anabasine by Isocyanide-Based Multicomponent Reactions
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2012
gro.hasfulltextNo Full Text
gro.griffith.authorKrasavin, Mikhail


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record