dc.contributor.author | Sandulenko, Y. | |
dc.contributor.author | Krasavin, Mikhail | |
dc.date.accessioned | 2017-05-03T15:58:30Z | |
dc.date.available | 2017-05-03T15:58:30Z | |
dc.date.issued | 2012 | |
dc.date.modified | 2013-06-20T04:07:52Z | |
dc.identifier.issn | 00093122 | |
dc.identifier.doi | 10.1007/s10593-012-1033-z | |
dc.identifier.uri | http://hdl.handle.net/10072/51699 | |
dc.description.abstract | Anabasine served as a starting material for the synthesis of two series of novel, drug-like compounds. On the one hand, anabasine was subjected to a direct Chichibabin amination and elaborated into medicinally relevant, racemic 6-(piperidin-2-yl)imidazo[1,2-a]pyridines via the Groebke-Blackburn reaction. On the other hand, anabasine was used as an amine for the Ugi reaction to provide novel non-racemic anabasine-containing 2-[(2-pyridin-3-yl)piperidin-1-yl]acetamide peptidomimetics with high diastereoselectivity. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Springer | |
dc.publisher.place | United States | |
dc.relation.ispartofstudentpublication | N | |
dc.relation.ispartofpagefrom | 606 | |
dc.relation.ispartofpageto | 612 | |
dc.relation.ispartofissue | 4 | |
dc.relation.ispartofjournal | Chemistry of Heterocyclic Ccompounds | |
dc.relation.ispartofvolume | 48 | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Medicinal and Biomolecular Chemistry not elsewhere classified | |
dc.subject.fieldofresearch | Organic Chemistry | |
dc.subject.fieldofresearchcode | 030499 | |
dc.subject.fieldofresearchcode | 0305 | |
dc.title | Natural Products as Templates for Bioactive Compound Libraries. 3. Novel Heterocycles and Peptidomimetics Generated from Anabasine by Isocyanide-Based Multicomponent Reactions | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.date.issued | 2012 | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Krasavin, Mikhail | |