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dc.contributor.authorPerchyonok, Tamara
dc.contributor.authorOberholzer, Theunis
dc.date.accessioned2017-05-29T12:33:53Z
dc.date.available2017-05-29T12:33:53Z
dc.date.issued2012
dc.date.modified2013-06-26T02:43:11Z
dc.identifier.issn18755348
dc.identifier.doi10.2174/138527212803520119
dc.identifier.urihttp://hdl.handle.net/10072/51903
dc.description.abstractCyclodextrins are cyclic oligomers of glucose that can form water-soluble inclusion complexes with small molecules and portions of large compounds. These biocompatible, cyclic oligosaccharides do not elicit immune responses and have low toxicities in animals and humans. Cyclodextrins are used in pharmaceutical applications for numerous purposes, including improving the bioavailability of drugs. Current cyclodextrin-based therapeutics are described and possible future applications discussed with particular focus on oral drug administration. This article focuses on development of in vitro reliable and simple prototypes for oral drug delivery by combing chemical, structural and pharmacological knowledge available to date in order to create an optimal oral drug delivery system based on modified cyclodextrins. Practical in vitro model is also demonstrated.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherBentham Science Publishers Ltd.
dc.publisher.placeNetherlands
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom2365
dc.relation.ispartofpageto2378
dc.relation.ispartofissue20
dc.relation.ispartofjournalCurrent Organic Chemistry
dc.relation.ispartofvolume16
dc.rights.retentionY
dc.subject.fieldofresearchOrganic Chemistry not elsewhere classified
dc.subject.fieldofresearchOrganic Chemistry
dc.subject.fieldofresearchcode030599
dc.subject.fieldofresearchcode0305
dc.titleCyclodextrins as Oral Drug Carrier Molecular Devices: Origins, Reasons and In-vitro Model Applications
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Health, School of Dentistry and Oral Health
gro.date.issued2012
gro.hasfulltextNo Full Text
gro.griffith.authorOberholzer, Theunis
gro.griffith.authorPerchyonok, Tamara


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    Contains articles published by Griffith authors in scholarly journals.

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