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  • Root discolouration following short-term application of steroid medicaments containing clindamycin, doxycycline or demeclocycline

    Author(s)
    Chen, Belinda Kuan-Jung
    George, Roy
    Walsh, Laurence James
    Griffith University Author(s)
    George, Roy
    Year published
    2012
    Metadata
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    Abstract
    Discolouration of teeth following application of intra-canal antibiotic pastes is a clinical concern. This laboratory study compared the extent of tooth discolouration from three antibiotic pastes over 4 weeks. A total of 120 root samples were prepared and the canals filled with either Ledermix (demeclocyline), Odontopaste (clindamycin) or DoxyPaste (doxycycline). Roots were photographed before and 2 or 4 weeks after incubation at 37àand 100% humidity in complete darkness in opaque containers. Digital images were standardised and assessed for changes in luminosity. Ledermix paste caused the most discolouration of the three, ...
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    Discolouration of teeth following application of intra-canal antibiotic pastes is a clinical concern. This laboratory study compared the extent of tooth discolouration from three antibiotic pastes over 4 weeks. A total of 120 root samples were prepared and the canals filled with either Ledermix (demeclocyline), Odontopaste (clindamycin) or DoxyPaste (doxycycline). Roots were photographed before and 2 or 4 weeks after incubation at 37àand 100% humidity in complete darkness in opaque containers. Digital images were standardised and assessed for changes in luminosity. Ledermix paste caused the most discolouration of the three, at both 2 and 4 weeks. There was no significant difference between DoxyPaste and Odontopaste at 2 weeks, whereas at 4 weeks, DoxyPaste caused a greater decrease in luminosity (P < 0.05), darkening more over the second 2-week interval than treatment with Odontopaste (P < 0.05). Under zero light conditions, staining with Ledermix can still occur; indicating non-light-based chemical reactions in the staining process. Doxycycline containing intra-canal medicaments caused less staining despite being a tetracycline-based medicament.
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    Journal Title
    Australian Endodontic Journal
    Volume
    38
    Issue
    3
    DOI
    https://doi.org/10.1111/aej.12000
    Subject
    Dentistry
    Endodontics
    Publication URI
    http://hdl.handle.net/10072/52630
    Collection
    • Journal articles

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