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dc.contributor.authorKoh, Wei Hang
dc.contributor.authorLok, Khoi Seng
dc.contributor.authorNam-Trung, Nguyen
dc.contributor.editorMalcolm J. Andrews
dc.date.accessioned2017-05-03T16:14:43Z
dc.date.available2017-05-03T16:14:43Z
dc.date.issued2013
dc.date.modified2013-08-20T00:14:30Z
dc.identifier.issn0098-2202
dc.identifier.doi10.1115/1.4023443
dc.identifier.urihttp://hdl.handle.net/10072/52666
dc.description.abstractThis paper reports the design and investigation of a digital micro magnetofluidic platform for lab-on-a-chip applications. The platform allows a ferrofluid droplet to be driven along a preprogrammed path. The platform consists of a programmable x-y-positioning stage, a permanent magnet and a glass plate coated with a thin layer of Teflon. First, the actuation of a stand-alone water-based ferrofluid droplet was investigated. Circular, rectangular, triangular and number-eight-shape trajectories were tested and analyzed. The speed of the droplet is evaluated from the position data of the black ferrofluid using a customized MATLAB program. The results show that better positioning accuracy and steady movement can be achieved with smooth trajectories. Next, the ferrofluid droplet as the driving engine for a cargo of other diamagnetic liquid droplets is demonstrated. The characteristics of different cargo volumes are investigated. Due to the liquid/liquid cohesion, a large cargo of five times the volume of a 3-uL ferrofluid droplet can be transported. If the cargo is larger than the driving ferrofluid droplet, the liquid system forms a long trail that faithfully follows the preprogrammed path. Various mixing experiments were carried out. The effectiveness of mixing in this system is demonstrated with a titration test as well as a chemiluminescence assay. The platform shows a robust, simple and flexible concept for implementing a complex analysis protocol with multiple reaction steps.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherA S M E International
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom021302-1
dc.relation.ispartofpageto021302-6
dc.relation.ispartofissue2
dc.relation.ispartofjournalJournal of Fluids Engineering
dc.relation.ispartofvolume135
dc.rights.retentionY
dc.subject.fieldofresearchFluid Physics
dc.subject.fieldofresearchBiomedical Instrumentation
dc.subject.fieldofresearchMicroelectromechanical Systems (MEMS)
dc.subject.fieldofresearchEngineering
dc.subject.fieldofresearchcode020303
dc.subject.fieldofresearchcode090303
dc.subject.fieldofresearchcode091306
dc.subject.fieldofresearchcode09
dc.titleA Digital Micro Magnetofluidic Platform For Lab-on-a-Chip Applications
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyrightSelf-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the authors for more information.
gro.date.issued2013
gro.hasfulltextNo Full Text
gro.griffith.authorNguyen, Nam-Trung


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