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  • Measuring protein concentration with entangled photons

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    Author(s)
    Crespi, Andrea
    Lobino, Mirko
    Matthews, Jonathan CF
    Politi, Alberto
    Neal, Chris R
    Ramponi, Roberta
    Osellame, Roberto
    O'Brien, Jeremy L
    Griffith University Author(s)
    Lobino, Mirko
    Year published
    2012
    Metadata
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    Abstract
    Optical interferometry is amongst the most sensitive techniques for precision measurement. By increasing the light intensity, a more precise measurement can usually be made. However, if the sample is light sensitive entangled states can achieve the same precision with less exposure. This concept has been demonstrated in measurements of known optical components. Here, we use two-photon entangled states to measure the concentration of a blood protein in an aqueous buffer solution. We use an opto-fluidic device that couples a waveguide interferometer with a microfluidic channel. These results point the way to practical applications ...
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    Optical interferometry is amongst the most sensitive techniques for precision measurement. By increasing the light intensity, a more precise measurement can usually be made. However, if the sample is light sensitive entangled states can achieve the same precision with less exposure. This concept has been demonstrated in measurements of known optical components. Here, we use two-photon entangled states to measure the concentration of a blood protein in an aqueous buffer solution. We use an opto-fluidic device that couples a waveguide interferometer with a microfluidic channel. These results point the way to practical applications of quantum metrology to light sensitive samples.
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    Journal Title
    Applied Physics Letters
    Volume
    100
    DOI
    https://doi.org/10.1063/1.4724105
    Copyright Statement
    © 2012 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Vol. 100, pp. 233704-1-233704-4 and may be found at dx.doi.org/10.1063/1.472410.
    Subject
    Physical sciences
    Quantum optics and quantum optomechanics
    Biological physics
    Engineering
    Publication URI
    http://hdl.handle.net/10072/53128
    Collection
    • Journal articles

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