Measuring protein concentration with entangled photons

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Author(s)
Crespi, Andrea
Lobino, Mirko
Matthews, Jonathan CF
Politi, Alberto
Neal, Chris R
Ramponi, Roberta
Osellame, Roberto
O'Brien, Jeremy L
Griffith University Author(s)
Year published
2012
Metadata
Show full item recordAbstract
Optical interferometry is amongst the most sensitive techniques for precision measurement. By increasing the light intensity, a more precise measurement can usually be made. However, if the sample is light sensitive entangled states can achieve the same precision with less exposure. This concept has been demonstrated in measurements of known optical components. Here, we use two-photon entangled states to measure the concentration of a blood protein in an aqueous buffer solution. We use an opto-fluidic device that couples a waveguide interferometer with a microfluidic channel. These results point the way to practical applications ...
View more >Optical interferometry is amongst the most sensitive techniques for precision measurement. By increasing the light intensity, a more precise measurement can usually be made. However, if the sample is light sensitive entangled states can achieve the same precision with less exposure. This concept has been demonstrated in measurements of known optical components. Here, we use two-photon entangled states to measure the concentration of a blood protein in an aqueous buffer solution. We use an opto-fluidic device that couples a waveguide interferometer with a microfluidic channel. These results point the way to practical applications of quantum metrology to light sensitive samples.
View less >
View more >Optical interferometry is amongst the most sensitive techniques for precision measurement. By increasing the light intensity, a more precise measurement can usually be made. However, if the sample is light sensitive entangled states can achieve the same precision with less exposure. This concept has been demonstrated in measurements of known optical components. Here, we use two-photon entangled states to measure the concentration of a blood protein in an aqueous buffer solution. We use an opto-fluidic device that couples a waveguide interferometer with a microfluidic channel. These results point the way to practical applications of quantum metrology to light sensitive samples.
View less >
Journal Title
Applied Physics Letters
Volume
100
Copyright Statement
© 2012 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Vol. 100, pp. 233704-1-233704-4 and may be found at dx.doi.org/10.1063/1.472410.
Subject
Physical sciences
Quantum optics and quantum optomechanics
Biological physics
Engineering