dc.contributor.author | Kularatna, Sanjeewa | |
dc.contributor.author | Whitty, Jennifer A | |
dc.contributor.author | Johnson, Newell W | |
dc.contributor.author | Scuffham, Paul A | |
dc.date.accessioned | 2017-05-03T14:21:09Z | |
dc.date.available | 2017-05-03T14:21:09Z | |
dc.date.issued | 2013 | |
dc.date.modified | 2014-01-31T03:36:55Z | |
dc.identifier.issn | 1477-7525 | |
dc.identifier.doi | 10.1186/1477-7525-11-149 | |
dc.identifier.uri | http://hdl.handle.net/10072/56300 | |
dc.description.abstract | Background Economic evaluations to inform decisions about allocation of health resources are scarce in Low and Middle Income Countries, including in Sri Lanka. This is in part due to a lack of country-specific utility weights, which are necessary to derive appropriate Quality Adjusted Life Years. The EQ-5D-3L, a generic multi-attribute instrument (MAUI), is most widely used to measure and value health states in high income countries; nevertheless, the sensitivity of generic MAUIs has been criticised in some conditions such as cancer. This article describes a protocol to produce both a generic EQ-5D-3L and cancer specific EORTC-8D utility index in Sri Lanka. Method EQ-5D-3L and EORTC-8D health states will be valued using the Time Trade-Off technique, by a representative population sample (n?=?780 invited) identified using stratified multi-stage cluster sampling with probability proportionate to size method. Households will be randomly selected within 30 clusters across four districts; one adult (=18 years) within each household will be selected using the Kish grid method. Data will be collected via face-to-face interview, with a Time Trade-Off board employed as a visual aid. Of the 243 EQ-5D-3L and 81,290 EORTC-8D health states, 196 and 84 respectively will be directly valued. In EQ-5D-3L, all health states that combine level 3 on mobility with either level 1 on usual activities or self-care were excluded. Each participant will first complete the EQ-5D-3L, rank and value 14 EQ-5D-3L states (plus the worst health state and "immediate death"), and then rank and value seven EORTC-8D states (plus "immediate death"). Participant demographic and health characteristics will be also collected. Regression models will be fitted to estimate utility indices for EQ-5D-3L and EORTC-8D health states for Sri Lanka. The dependent variable will be the utility value. Different specifications of independent variables will be derived from the ordinal EQ-5D-3L to test for the best-fitting model. Discussion In Sri Lanka, a LMIC health state valuation will have to be carried out using face to face interview instead of online methods. The proposed study will provide the first country-specific health state valuations for Sri Lanka, and one of the first valuations to be completed in a South Asian Country. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.format.extent | 196639 bytes | |
dc.format.mimetype | application/pdf | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | BioMed Central | |
dc.publisher.place | United Kingdom | |
dc.relation.ispartofstudentpublication | N | |
dc.relation.ispartofpagefrom | 149-1 | |
dc.relation.ispartofpageto | 149-8 | |
dc.relation.ispartofjournal | Health and Quality of Life Outcomes | |
dc.relation.ispartofvolume | 11 | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Health services and systems | |
dc.subject.fieldofresearch | Public health | |
dc.subject.fieldofresearchcode | 4203 | |
dc.subject.fieldofresearchcode | 4206 | |
dc.title | Study protocol for valuing EQ-5D-3L and EORTC-8D health states in a representative population sample in Sri Lanka | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
dcterms.license | http://creativecommons.org/licenses/by/2.0 | |
gro.faculty | Griffith Health, School of Medicine | |
gro.description.notepublic | Page numbers are not for citation purposes. Instead, this article has the unique article number of 149. | |
gro.rights.copyright | © 2013 Kularatna et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |
gro.date.issued | 2013 | |
gro.hasfulltext | Full Text | |
gro.griffith.author | Johnson, Newell W. | |
gro.griffith.author | Scuffham, Paul A. | |