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dc.contributor.authorPryor, David I
dc.contributor.authorPorceddu, Sandro V
dc.contributor.authorScuffham, Paul A
dc.contributor.authorWhitty, Jennifer A
dc.contributor.authorThomas, Paul A
dc.contributor.authorBurmeister, Bryan H
dc.date.accessioned2017-05-03T14:21:08Z
dc.date.available2017-05-03T14:21:08Z
dc.date.issued2013
dc.date.modified2014-01-31T04:21:01Z
dc.identifier.issn1043-3074
dc.identifier.doi10.1002/hed.23108
dc.identifier.urihttp://hdl.handle.net/10072/56324
dc.description.abstractBackground The aim of this economic analysis was to model different strategies using pre-treatment nodal stage or nodal response assessment with CT or positron emission tomography (PET)/CT to determine the need for neck dissection. Methods A cost-minimization analysis was developed on the basis of probability data from a prospective study of PET-guided management of the neck in patients achieving a complete response at the primary site. Costs were derived from our institution's activity-based clinical costing system. The effect of uncertainty was tested with sensitivity and scenario analyses including nationally representative cost data. Results Strategies incorporating PET had a 7% rate for neck dissection compared with 44% for CT-guided and 90% for planned neck dissection. The cost per patient was A$16,502 for planned neck dissection, A$8014 for CT-guided, and A$2573 for PET-guided. A policy with PET used only for incomplete response on CT was the least-cost strategy (A$2111). Policies incorporating PET remained the most efficient for all sensitivity/scenario analyses. Conclusion The incorporation of PET/CT into nodal response assessment significantly reduced the number of unnecessary neck dissections and generated considerable cost savings in our cohort. 頲012 Wiley Periodicals, Inc. Head Neck, 2013
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherJohn Wiley & Sons
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1287
dc.relation.ispartofpageto1294
dc.relation.ispartofissue9
dc.relation.ispartofjournalHead & Neck
dc.relation.ispartofvolume35
dc.rights.retentionY
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode3203
dc.titleEconomic Analysis of FDG-PET-Guided Management of the Neck after Primary Chemoradiotherapy for Node-Positive Head and Neck Squamous Cell Carcinoma
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2013
gro.hasfulltextNo Full Text
gro.griffith.authorScuffham, Paul A.


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