dc.contributor.author | Mosavi, Reza | |
dc.contributor.author | Arababadi, Mohammad Kazemi | |
dc.contributor.author | Hassanshahi, Gholamhossein | |
dc.contributor.author | Azin, Hossein | |
dc.contributor.author | Araste, Majid | |
dc.contributor.author | Salehabad, Vajihe Akbarpour | |
dc.contributor.author | Vazirinejad, Reza | |
dc.contributor.author | Pourali, Reza | |
dc.contributor.author | Hakimi, Hamid | |
dc.contributor.author | Kennedy, Derek | |
dc.date.accessioned | 2017-05-03T11:12:40Z | |
dc.date.available | 2017-05-03T11:12:40Z | |
dc.date.issued | 2013 | |
dc.date.modified | 2014-02-05T21:59:06Z | |
dc.identifier.issn | 0007-5027 | |
dc.identifier.uri | http://hdl.handle.net/10072/56476 | |
dc.description.abstract | Objective: To investigate the association between multiple sclerosis (MS) and polymorphisms in intron 8 and exon 9 of the vitamin D receptor (VDR) gene. Methods: Blood samples were collected from 100 patients with MS and 100 healthy control individuals in ethylenediaminetetraacetic acid (EDTA) tubes. DNA was extracted and analyzed via polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) for polymorphisms within the VDR. Demographic data were also collected via a questionnaire designed specifically for this study. Results: Our results showed a significant difference between the A/A genotype and between the A and a alleles of intron 8 of VDR; however, no differences were observed in the other studied alleles. Conclusion: VDR and its functional polymorphisms may be associated with MS. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | American Society for Clinical Pathology | |
dc.publisher.place | United States | |
dc.publisher.uri | http://labmed.ascpjournals.org/content/44/3/215.abstract | |
dc.relation.ispartofstudentpublication | N | |
dc.relation.ispartofpagefrom | 215 | |
dc.relation.ispartofpageto | 219 | |
dc.relation.ispartofissue | 3 | |
dc.relation.ispartofjournal | Laboratory Medicine | |
dc.relation.ispartofvolume | 44 | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Neurology and neuromuscular diseases | |
dc.subject.fieldofresearchcode | 320905 | |
dc.title | Association of a Polymorphism Within Intron 8 But Not Exon 9 of the Vitamin D Receptor in Patients With Multiple Sclerosis of Southeastern Iranian Ethnicity | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.rights.copyright | Self-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the authors for more information. | |
gro.date.issued | 2013 | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Kennedy, Derek D. | |