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dc.contributor.authorMosavi, Reza
dc.contributor.authorArababadi, Mohammad Kazemi
dc.contributor.authorHassanshahi, Gholamhossein
dc.contributor.authorAzin, Hossein
dc.contributor.authorAraste, Majid
dc.contributor.authorSalehabad, Vajihe Akbarpour
dc.contributor.authorVazirinejad, Reza
dc.contributor.authorPourali, Reza
dc.contributor.authorHakimi, Hamid
dc.contributor.authorKennedy, Derek
dc.date.accessioned2017-05-03T11:12:40Z
dc.date.available2017-05-03T11:12:40Z
dc.date.issued2013
dc.date.modified2014-02-05T21:59:06Z
dc.identifier.issn0007-5027
dc.identifier.urihttp://hdl.handle.net/10072/56476
dc.description.abstractObjective: To investigate the association between multiple sclerosis (MS) and polymorphisms in intron 8 and exon 9 of the vitamin D receptor (VDR) gene. Methods: Blood samples were collected from 100 patients with MS and 100 healthy control individuals in ethylenediaminetetraacetic acid (EDTA) tubes. DNA was extracted and analyzed via polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) for polymorphisms within the VDR. Demographic data were also collected via a questionnaire designed specifically for this study. Results: Our results showed a significant difference between the A/A genotype and between the A and a alleles of intron 8 of VDR; however, no differences were observed in the other studied alleles. Conclusion: VDR and its functional polymorphisms may be associated with MS.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherAmerican Society for Clinical Pathology
dc.publisher.placeUnited States
dc.publisher.urihttp://labmed.ascpjournals.org/content/44/3/215.abstract
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom215
dc.relation.ispartofpageto219
dc.relation.ispartofissue3
dc.relation.ispartofjournalLaboratory Medicine
dc.relation.ispartofvolume44
dc.rights.retentionY
dc.subject.fieldofresearchNeurology and neuromuscular diseases
dc.subject.fieldofresearchcode320905
dc.titleAssociation of a Polymorphism Within Intron 8 But Not Exon 9 of the Vitamin D Receptor in Patients With Multiple Sclerosis of Southeastern Iranian Ethnicity
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyrightSelf-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the authors for more information.
gro.date.issued2013
gro.hasfulltextNo Full Text
gro.griffith.authorKennedy, Derek D.


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