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  • The nature and extent of working memory dysfunction in schizophrenia

    Author
    Cao, Xiao-yan
    Li, Zhi
    M. Metcalfe, Hugo
    Yang, Tian-xiao
    Tan, Shu-ping
    Wang, Ya
    Hong, Xiao-hong
    Li, Zhan-Jiang
    Yu, Xin
    F. C. Cheung, Eric
    Neumann, David
    Shum, David
    C. K. Chan, Raymond
    Year published
    2013
    Metadata
    Show full item record
    Abstract
    This study aimed to examine verbal and visual-spatial working memory (WM) dysfunction in patients with schizophrenia. We compared 60 patients with schizophrenia with 57 healthy controls (matched for age, educational level, and IQ) on three WM tasks. Patients with schizophrenia performed significantly more poorly than healthy controls on verbal, visual, and spatial WM tests. Moreover, WM deficits were inversely associated with both the positive and negative symptoms of the patients. Taken together, these findings suggest that there are pervasive WM impairments in patients with schizophrenia. In addition, clinical features may ...
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    This study aimed to examine verbal and visual-spatial working memory (WM) dysfunction in patients with schizophrenia. We compared 60 patients with schizophrenia with 57 healthy controls (matched for age, educational level, and IQ) on three WM tasks. Patients with schizophrenia performed significantly more poorly than healthy controls on verbal, visual, and spatial WM tests. Moreover, WM deficits were inversely associated with both the positive and negative symptoms of the patients. Taken together, these findings suggest that there are pervasive WM impairments in patients with schizophrenia. In addition, clinical features may play a significant role in the expression of WM deficits.
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    Journal Title
    PsyCh Journal
    Volume
    2
    Issue
    3
    DOI
    https://doi.org/10.1002/pchj.30
    Subject
    Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)
    Publication URI
    http://hdl.handle.net/10072/56927
    Collection
    • Journal articles

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