Isolation of adult stem cells from the human olfactory mucosa
Author(s)
Feron, Francois
Perry, Chris
Girard, Stephane D
Mackay-Sim, Alan
Griffith University Author(s)
Year published
2013
Metadata
Show full item recordAbstract
The olfactory mucosa, located in the nasal cavity, is the only nervous tissue that is exposed to the external environment and easily accessible in every living individual. In addition, this organ is home of a continuing neurogenesis that is sustained by a large population of stem cells. Here, we describe a method for biopsying olfactory mucosa from human nasal cavities and isolating multipotent adult stem cells that can be used to either identify biomarkers in brain disorders or repair the pathological/traumatized nervous system.The olfactory mucosa, located in the nasal cavity, is the only nervous tissue that is exposed to the external environment and easily accessible in every living individual. In addition, this organ is home of a continuing neurogenesis that is sustained by a large population of stem cells. Here, we describe a method for biopsying olfactory mucosa from human nasal cavities and isolating multipotent adult stem cells that can be used to either identify biomarkers in brain disorders or repair the pathological/traumatized nervous system.
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Journal Title
Methods in Molecular Biology
Volume
1059
Subject
Other chemical sciences
Biochemistry and cell biology
Neurology and neuromuscular diseases