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  • A Multicenter, Randomized Trial of a Nurse-Led, Home-Based Intervention for Optimal Secondary Cardiac Prevention Suggests Some Benefits for Men but Not for Women: The Young at Heart Study.

    Author(s)
    Carrington, Melinda J
    Chan, Yih-Kai
    Calderone, Alicia
    Scuffham, Paul A
    Esterman, Adrian
    Goldstein, Stan
    Stewart, Simon
    Griffith University Author(s)
    Scuffham, Paul A.
    Year published
    2013
    Metadata
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    Abstract
    Background-We examined the impact of a prolonged secondary prevention program on recurrent hospitalization in cardiac patients with private health insurance. Methods and Results-The Young at Heart multicenter, randomized, controlled trial compared usual postdischarge care (UC) with nurse-led, home-based intervention (HBI). The primary end point was rate of all-cause hospital stay (31.5ᷮ5 months follow-up). In total, 602 patients (aged 70ᱰ years, 72% men) were randomized to UC (n=296) or HBI (n=306, 96% received =1 home visit). Overall, 42 patients (7.0%) died, and 492 patients (82%) accumulated 2397 all-cause hospitalizations ...
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    Background-We examined the impact of a prolonged secondary prevention program on recurrent hospitalization in cardiac patients with private health insurance. Methods and Results-The Young at Heart multicenter, randomized, controlled trial compared usual postdischarge care (UC) with nurse-led, home-based intervention (HBI). The primary end point was rate of all-cause hospital stay (31.5ᷮ5 months follow-up). In total, 602 patients (aged 70ᱰ years, 72% men) were randomized to UC (n=296) or HBI (n=306, 96% received =1 home visit). Overall, 42 patients (7.0%) died, and 492 patients (82%) accumulated 2397 all-cause hospitalizations associated with 10?258 hospital days costing >$17 million. There were minimal group differences (HBI versus UC) in the primary end point of all-cause hospital stay (5405 versus 4853 days; median [interquartile range], 0.08 [0.03-0.17] versus 0.07 [0.03-0.13]/patient per month). There were similar trends with respect to all hospitalizations (1197 versus 1200; P=0.802) and associated costs ($8.66 versus $8.58 million; P=0.375). At 2 years, however, more HBI versus UC (39% versus 27%; odds ratio, 1.67; 95% confidence interval, 1.15-2.41; P=0.007) patients were assessed as stable and optimally managed. For women, HBI outcomes were predominantly worse than UC outcomes. In men, HBI was associated with reduced risk of cardiovascular hospitalization (adjusted hazard ratio, 0.68; 95% confidence interval, 0.46-0.99; P=0.044) with less cardiovascular hospitalizations (192 versus 269; P=0.054) and costs ($2.49 versus $3.53 million; P=0.046). Conclusions-HBI did not reduce recurrent all-cause hospitalization compared with UC in privately insured cardiac patients overall. However, it did convey some benefits in cardiac outcomes for men.
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    Journal Title
    Circulation Cardiovascular Quality and Outcomes
    Volume
    6
    Issue
    4
    DOI
    https://doi.org/10.1161/CIRCOUTCOMES.111.000006
    Subject
    Cardiovascular medicine and haematology
    Publication URI
    http://hdl.handle.net/10072/57370
    Collection
    • Journal articles

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