Dictamins A–C, three unprecedented apotirucallane-type trinortriterpenoids from Dictamnus dasycarpus
Author(s)
Chen, Hong-Yu
Hu, Zhen-Yi
Tang, Chun-Ping
Quinn, Ronald J
Feng, Yunjiang
Yao, Sheng
Ye, Yang
Year published
2013
Metadata
Show full item recordAbstract
Dictamins A-C, the first known examples of apotirucallane-type trinortriterpenoids, were isolated from the root bark of Dictamnus dasycarpus. Their structures and relative configurations were elucidated on the basis of extensive NMR and single-crystal X-ray diffraction analyses. Such compounds might be the key C5 side chain intermediates for an alternative degradation process from protolimonoids (C8 side chain) to limonoids (C4 side chain), bridging an oxidative cleavage biogenetic pathway between these two classes of structurally diverse triterpenoids.Dictamins A-C, the first known examples of apotirucallane-type trinortriterpenoids, were isolated from the root bark of Dictamnus dasycarpus. Their structures and relative configurations were elucidated on the basis of extensive NMR and single-crystal X-ray diffraction analyses. Such compounds might be the key C5 side chain intermediates for an alternative degradation process from protolimonoids (C8 side chain) to limonoids (C4 side chain), bridging an oxidative cleavage biogenetic pathway between these two classes of structurally diverse triterpenoids.
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Journal Title
Tetrahedron Letters
Volume
54
Issue
32
Subject
Medicinal and biomolecular chemistry
Medicinal and biomolecular chemistry not elsewhere classified
Organic chemistry
Biochemistry and cell biology