4-amino-2,6-dichloro-5-nitropyrimidine

Abstract

The title compound, C4H2Cl2N4O2, is a key intermediate in the synthesis of a purine scaffold, as nucleophilic substitution of the chlorides allows access to a diverse array of potentially biologically active compounds. The mol�ules exhibit an intramolecular N-HO hydrogen bond between the ortho amino and nitro substituents. Pairs of mol�ules associate across a crystallographic centre of symmetry through N-HN intermolecular hydrogen bonding between the ortho amino group and the ring N atom.