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dc.contributor.authorHart, Melissa
dc.contributor.authorWilcken, Bridget
dc.contributor.authorT. Williams, Lauren
dc.contributor.authorSibbritt, David
dc.contributor.authorNunn, Kenneth Patrick
dc.date.accessioned2017-05-16T12:31:07Z
dc.date.available2017-05-16T12:31:07Z
dc.date.issued2013
dc.date.modified2014-04-03T03:59:44Z
dc.identifier.issn21662630
dc.identifier.doi10.1080/21662630.2013.742978
dc.identifier.urihttp://hdl.handle.net/10072/57797
dc.description.abstractAnorexia nervosa (AN) is accompanied by an increased frequency of pre-morbid anxiety. Anxiety disorders are associated with increased brain activity of catecholamines, especially noradrenaline. It has been hypothesized that noradrenergic dysregulation may be a major factor in the causation of AN. In this article, we explore this hypothesis and how it might account for the reduction of anxiety found in starvation, the increase in anxiety found with re-feeding, and thus the reinforcement of anxiety by re-feeding. We propose that alleviation of this dysregulation through the noradrenaline precursor (tyrosine) supplementation, leading to saturation of supply, may alleviate some of the pathological changes found in AN. We consider how the hypothesis might be investigated. The success of tyrosine supplementation would have important implications from theoretical, research and clinical perspectives.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.publisherRoutledge
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom161
dc.relation.ispartofpageto168
dc.relation.ispartofissue2
dc.relation.ispartofjournalAdvances in Eating Disorders
dc.relation.ispartofvolume1
dc.rights.retentionY
dc.subject.fieldofresearchNutrition and Dietetics not elsewhere classified
dc.subject.fieldofresearchMedical Physiology
dc.subject.fieldofresearchPublic Health and Health Services
dc.subject.fieldofresearchPsychology
dc.subject.fieldofresearchcode111199
dc.subject.fieldofresearchcode1116
dc.subject.fieldofresearchcode1117
dc.subject.fieldofresearchcode1701
dc.titleTyrosine supplementation as an adjunct treatment in anorexia nervosa – a noradrenergic repletion hypothesis
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2013
gro.hasfulltextNo Full Text
gro.griffith.authorWilliams, Lauren T.


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