X-ray structure of [3aR-[1(2S*,3R*,6Z,8S*),3aa,6a,7ab]]-1-[8-[[(t-butyl)diphenylsilyl]oxy]-3-hydroxy-2-methyl-1-oxo-6-nonenyl]hexahydro-8,8-dimethyl-3H-3a,6-methano-2,1-benzisothiazole-2,2-dioxide.
Author(s)
Garavelas, Agatha
Westman, Gunnar
Perlmutter, Patrick
Bratt, Katharina
Tiekink, Edward R. T.
Griffith University Author(s)
Year published
2001
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The title compd. (I), was studied as a part of a study into the influence of remote silyloxy groups upon intramol. oxymercurations of g-hydroxyalkenes. Alkene stereochem. and conformation at the allylic C are also believed to play important roles in controlling the diastereoselection of such processes. As compd. I underwent highly diastereoselective intramol. oxymercuration it was crit. for this study that its structure be established. Thus, the structure detn. reveals the configuration about the C2, C3 and C8 atoms as S, R and S, resp., and the stereochem. about the C6=C7 bond as Z. The Si atom exists in a distorted ...
View more >The title compd. (I), was studied as a part of a study into the influence of remote silyloxy groups upon intramol. oxymercurations of g-hydroxyalkenes. Alkene stereochem. and conformation at the allylic C are also believed to play important roles in controlling the diastereoselection of such processes. As compd. I underwent highly diastereoselective intramol. oxymercuration it was crit. for this study that its structure be established. Thus, the structure detn. reveals the configuration about the C2, C3 and C8 atoms as S, R and S, resp., and the stereochem. about the C6=C7 bond as Z. The Si atom exists in a distorted tetrahedral geometry with angles in the range 103.22(18) to 115.58(19)° with the smallest and largest angles involving the tert-Bu group.
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View more >The title compd. (I), was studied as a part of a study into the influence of remote silyloxy groups upon intramol. oxymercurations of g-hydroxyalkenes. Alkene stereochem. and conformation at the allylic C are also believed to play important roles in controlling the diastereoselection of such processes. As compd. I underwent highly diastereoselective intramol. oxymercuration it was crit. for this study that its structure be established. Thus, the structure detn. reveals the configuration about the C2, C3 and C8 atoms as S, R and S, resp., and the stereochem. about the C6=C7 bond as Z. The Si atom exists in a distorted tetrahedral geometry with angles in the range 103.22(18) to 115.58(19)° with the smallest and largest angles involving the tert-Bu group.
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Journal Title
Main Group Metal Chemistry
Volume
24
Issue
5
Subject
Inorganic Chemistry
Other Chemical Sciences