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dc.contributor.authorBatzloff, Michael R.en_US
dc.contributor.authorPandey, Manishaen_US
dc.contributor.authorOlive, Colleenen_US
dc.contributor.authorGood, Michael F.en_US
dc.date.accessioned2017-05-03T14:54:14Z
dc.date.available2017-05-03T14:54:14Z
dc.date.issued2006en_US
dc.date.modified2014-04-24T02:28:15Z
dc.identifier.issn0257277Xen_US
dc.identifier.doi10.1385/IR:35:3:233en_US
dc.identifier.urihttp://hdl.handle.net/10072/58864
dc.description.abstractRheumatic fever (RF) and rheumatic heart disease (RHD) are post-infectious complications of an infection (or repeated infection) with the Gram-positive bacterium Streptococcus pyogenes (also known as group A streptococcus, GAS). RF and RHD are global problems and affect many indigenous populations of developed countries and many developing countries. However, RF and RHD are only part of a larger spectrum of diseases caused by this organism. The development of a vaccine against GAS has primarily targeted the abundant cell-surface protein called the M-protein. This review focuses on different M-protein-based-subunit vaccine approaches and the different delivery technologies used to administer these vaccine candidates in preclinical studies.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.languageEnglishen_US
dc.publisherHumana Press, Inc.en_US
dc.publisher.placeUnited Statesen_US
dc.relation.ispartofstudentpublicationNen_US
dc.relation.ispartofpagefrom233en_US
dc.relation.ispartofpageto248en_US
dc.relation.ispartofissue3en_US
dc.relation.ispartofjournalImmunologic Researchen_US
dc.relation.ispartofvolume35en_US
dc.rights.retentionYen_US
dc.subject.fieldofresearchImmunology not elsewhere classifieden_US
dc.subject.fieldofresearchcode110799en_US
dc.titleAdvances in potential M-protein peptide-based vaccines for preventing rheumatic fever and rheumatic heart diseaseen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2006
gro.hasfulltextNo Full Text
gro.griffith.authorGood, Michael F.


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