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dc.contributor.authorJayasinghe, Rohan
dc.contributor.authorMarkham, Ryan
dc.contributor.authorAdsett, Geoffrey
dc.date.accessioned2014-02-12
dc.date.accessioned2014-06-03T02:53:01Z
dc.date.accessioned2017-03-02T00:20:22Z
dc.date.available2017-03-02T00:20:22Z
dc.date.issued2013
dc.date.modified2014-06-03T02:53:01Z
dc.identifier.issn0300-8495
dc.identifier.urihttp://hdl.handle.net/10072/59746
dc.description.abstractBackground Prasugrel and ticagrelor are two new antiplatelet agents being used in the management of acute coronary syndromes. The number of patients in the community managed on these medications is growing, and thus, it is essential that general practitioners have a good understanding of these agents and their evidence-based applications. Objective The pharmacokinetic and pharmacodynamic properties of common and new antiplatelet agents will be reviewed, along with the evidence supporting their use. Safety and side effect profiles will be discussed, and some common general practice case scenarios presented. Discussion Aspirin is still the mainstay of therapy in patients with acute coronary syndromes. The addition of clopidogrel, prasugrel or ticagrelor can reduce morbidity and mortality in selected patients. Patient factors including bleeding risk, renal function and time since coronary stent insertion must be reviewed before these agents are initiated and before making any changes to the medication regimen.
dc.description.peerreviewedNo
dc.description.publicationstatusYes
dc.format.extent97955 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherRoyal Australian College of General Practitioners
dc.publisher.placeAustralia
dc.publisher.urihttp://www.racgp.org.au/afp/2013/october/dual-antiplatelet-therapy/
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom702
dc.relation.ispartofpageto705
dc.relation.ispartofissue10
dc.relation.ispartofjournalAustralian Family Physician
dc.relation.ispartofvolume42
dc.rights.retentionY
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode3202
dc.titleDual antiplatelet therapy -- management in general practice.
dc.typeJournal article
dc.type.descriptionC2 - Articles (Other)
dc.type.codec2
gro.facultyGriffith Health Faculty
gro.rights.copyright© 2013 Australian Family Physician. Reproduced with permission. Permission to reproduce must be sought from the publisher, The Royal Australian College of General Practitioners.
gro.hasfulltextFull Text
gro.griffith.authorJayasinghe, Satyajit R.


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