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  • Improving the diagnosis, management, and outcomes of children with pneumonia: where are the gaps?

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    94719_1.pdf (419.0Kb)
    Author(s)
    Chang, AB
    Ooi, MH
    Perera, D
    Grimwood, K
    Griffith University Author(s)
    Grimwood, Keith
    Year published
    2013
    Metadata
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    Abstract
    Pneumonia is the greatest contributor to childhood mortality and morbidity in resource-poor regions, while in high-income countries it is one of the most common reasons for clinic attendance and hospitalization in this age group. Furthermore, pneumonia in children increases the risk of developing chronic pulmonary disorders in later adult life. While substantial advances in managing childhood pneumonia have been made, many issues remain, some of which are highlighted in this perspective. Multiple studies are required as many factors that influence outcomes, such as etiology, patient characteristics, and prevention strategies ...
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    Pneumonia is the greatest contributor to childhood mortality and morbidity in resource-poor regions, while in high-income countries it is one of the most common reasons for clinic attendance and hospitalization in this age group. Furthermore, pneumonia in children increases the risk of developing chronic pulmonary disorders in later adult life. While substantial advances in managing childhood pneumonia have been made, many issues remain, some of which are highlighted in this perspective. Multiple studies are required as many factors that influence outcomes, such as etiology, patient characteristics, and prevention strategies can vary between and within countries and regions. Also, outside of vaccine studies, most randomized controlled trials (RCTs) on pneumonia have been based in resource-poor countries where the primary aim is usually prevention of mortality. Few RCTs have focused on medium to long-term outcomes or prevention. We propose different tiers of primary outcomes, where in resource-rich countries medium to long-term sequelae should also be included and not just the length of hospitalization and readmission rates.
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    Journal Title
    Frontiers in Pediatrics
    Volume
    1
    Issue
    29
    DOI
    https://doi.org/10.3389/fped.2013.00029
    Copyright Statement
    © The Author(s) 2013. The attached file is reproduced here in accordance with the copyright policy of the publisher. For information about this journal please refer to the journal’s website or contact the authors.
    Subject
    Medical and Health Sciences not elsewhere classified
    Paediatrics and Reproductive Medicine
    Other Medical and Health Sciences
    Publication URI
    http://hdl.handle.net/10072/60114
    Collection
    • Journal articles

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