Tetrahydrofuran amino acids: b- and g-azidotetrahydrofurancarboxylic acid monomers derived from D-glucoheptonolactone as building blocks for b- and g-oligopeptides.

Abstract

The synthesis of both a β (L-allono) and a γ (D-allono) tetrahydrofuran azido acid from a single heptono sugar lactone as monomers for peptidomimetic oligomers is described.