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  • The clinical and MRI correlate of ischaemia in the ventromedial midbrain: Claude's syndrome

    Author(s)
    Broadley, SA
    Taylor, J
    Waddy, HM
    Thompson, PD
    Griffith University Author(s)
    Broadley, Simon
    Year published
    2001
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    Abstract
    The eponymous syndrome of Claude is caused by a lesion of the red nucleus and adjacent third nerve nucleus, resulting in the combination of an ipsilateral oculomotor palsy and contralateral ataxia. The MRI correlate of this syndrome has only occasionally been described. We present three cases with MRI findings which confirm the association of this clinical syndrome with infarction of the ventromedial midbrain. The coexistence of hypertension and small vessel ischaemia in two cases suggests this type of infarct may arise as a result of small vessel disease.The eponymous syndrome of Claude is caused by a lesion of the red nucleus and adjacent third nerve nucleus, resulting in the combination of an ipsilateral oculomotor palsy and contralateral ataxia. The MRI correlate of this syndrome has only occasionally been described. We present three cases with MRI findings which confirm the association of this clinical syndrome with infarction of the ventromedial midbrain. The coexistence of hypertension and small vessel ischaemia in two cases suggests this type of infarct may arise as a result of small vessel disease.
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    Journal Title
    Journal of Neurology
    Volume
    248
    Issue
    12
    DOI
    https://doi.org/10.1007/s004150170030
    Subject
    Clinical Sciences
    Neurosciences
    Publication URI
    http://hdl.handle.net/10072/60642
    Collection
    • Journal articles

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