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  • Prevention of neonatal group B streptococcus disease in the 21st centuryjpc_2203

    Author(s)
    Clifford, Vanessa
    Garland, Suzanne M
    Grimwood, Keith
    Griffith University Author(s)
    Grimwood, Keith
    Year published
    2012
    Metadata
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    Abstract
    There have been significant reductions in early-onset neonatal group B streptococcus (GBS) disease following implementation of maternal intrapartum antibiotic prophylaxis (IAP) policies. Nevertheless, GBS remains a leading cause of neonatal sepsis in Australia and New Zealand resulting in considerable morbidity and mortality, particularly among preterm infants. In the United States, the universal screening-based approach for identifying women for IAP results in apparently lower rates of early-onset neonatal GBS infection than risk-based assessment. In addition, IAP has altered the profile of newborn infants who develop ...
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    There have been significant reductions in early-onset neonatal group B streptococcus (GBS) disease following implementation of maternal intrapartum antibiotic prophylaxis (IAP) policies. Nevertheless, GBS remains a leading cause of neonatal sepsis in Australia and New Zealand resulting in considerable morbidity and mortality, particularly among preterm infants. In the United States, the universal screening-based approach for identifying women for IAP results in apparently lower rates of early-onset neonatal GBS infection than risk-based assessment. In addition, IAP has altered the profile of newborn infants who develop early-onset disease. Many affected infants lack the typical intrapartum risk factors for GBS infection, are born to mothers with a negative GBS screen or represent missed opportunities for prevention. Clinicians should remain alert for signs of sepsis in any newborn infant. We provide an update of GBS preventative management strategies in the perinatal period taking into account recent United States, Australian and New Zealand guidelines.
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    Journal Title
    Journal of Paediatrics and Child Health
    Volume
    48
    DOI
    https://doi.org/10.1111/j.1440-1754.2011.02203.x
    Subject
    Clinical sciences
    Reproductive medicine not elsewhere classified
    Publication URI
    http://hdl.handle.net/10072/60787
    Collection
    • Journal articles

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