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  • Engineering microfluidic concentration gradient generators for biological applications

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    91760_1.pdf (1.339Mb)
    Author(s)
    Toh, Alicia GG
    Wang, ZP
    Yang, Chun
    Nam-Trung, Nguyen
    Griffith University Author(s)
    Nguyen, Nam-Trung
    Year published
    2014
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    Abstract
    This paper reviews the latest developments in the design and fabrication of concentration gradient generators for microfluidics-based biological applications. New gradient generator designs and their underlying mass transport principles are discussed. The review provides a blueprint for design considerations of concentration gradients in different applications, specifically biological studies. The paper discusses the basic phenomena associated with microfluidic gradient generation and the different gradient generation modes used in static and dynamic biological assays. Finally, the paper summarizes all factors to consider ...
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    This paper reviews the latest developments in the design and fabrication of concentration gradient generators for microfluidics-based biological applications. New gradient generator designs and their underlying mass transport principles are discussed. The review provides a blueprint for design considerations of concentration gradients in different applications, specifically biological studies. The paper discusses the basic phenomena associated with microfluidic gradient generation and the different gradient generation modes used in static and dynamic biological assays. Finally, the paper summarizes all factors to consider when using concentration gradient generators and puts forward perspectives on the future development of these devices.
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    Journal Title
    Microfluidics and Nanofluidics
    Volume
    16
    Issue
    1-2
    DOI
    https://doi.org/10.1007/s10404-013-1236-3
    Copyright Statement
    © 2014 Springer Berlin Heidelberg. This is an electronic version of an article published in Microfluidics and Nanofluidics, Vol. 16(1-2), pp. 1-18, 2014. Microfluidics and Nanofluidics is available online at: http://link.springer.com/ with the open URL of your article.
    Subject
    Mechanical engineering
    Engineering practice and education not elsewhere classified
    Nanotechnology
    Nanoelectromechanical systems
    Publication URI
    http://hdl.handle.net/10072/61109
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    • Journal articles

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