Antiplasmodial Triterpenoids from the Fruits of Neem, Azadirachta indica

Author(s)
Chianese, G
Yerbanga, SR
Lucantoni, L
Habluetzel, A
Basilico, N
Taramelli, D
Fattorusso, E
Taglialatela-Scafati, O
Griffith University Author(s)
Year published
2010
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Abstract
Eight known and two new triterpenoid derivatives, neemfruitins A (9) and B (10), have been isolated from the fruits of neem, Azadirachta indica, a traditional antimalarial plant used by Asian and African populations. In vitro antiplasmodial tests evidenced a significant activity of the known gedunin and azadirone and the new neemfruitin A and provided useful information about the structure−antimalarial activity relationships in the limonoid class.
Journal Title
Journal of Natural Products
Volume
73
DOI
Copyright Statement
Self-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the authors for more information.
Subject
Biological Sciences not elsewhere classified
Chemical Sciences
Biological Sciences
Medical and Health Sciences
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