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dc.contributor.authorJohnston, Samantha C
dc.contributor.authorBrenu, Ekua W
dc.contributor.authorHardcastle, Sharni L
dc.contributor.authorHuth, Teilah K
dc.contributor.authorStaines, Donald R
dc.contributor.authorMarshall-Gradisnik, Sonya M
dc.date.accessioned2017-05-29T12:34:09Z
dc.date.available2017-05-29T12:34:09Z
dc.date.issued2014
dc.date.modified2014-08-07T00:11:38Z
dc.identifier.issn1477-7525
dc.identifier.doi10.1186/1477-7525-12-64
dc.identifier.urihttp://hdl.handle.net/10072/61961
dc.description.abstractBackground: Several diagnostic definitions are available for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) that varies significantly in their symptom criteria. This pilot study was conducted to determine whether simple biological and clinical measures differed between CFS/ME patients meeting the 1994 Centres for Disease Control and Prevention (CDC) criteria, the International Consensus Criteria (ICC), as well as healthy controls. Methods: A total of 45 CFS/ME patients and 30 healthy controls from the South East Queensland region of Australia provided a blood sample, reported on their current symptoms, as well as aspects of their physical and social health using the Short-Form Health Survey (SF-36), and the World Health Organisation Disability Adjustment Schedule 2.0 (WHO DAS 2.0). Differences were examined using independent sample t-testing. Results: Patients fulfilling the ICC definition reported significantly lower scores (p < 0.05) for physical functioning, physical role, bodily pain, and social functioning than those that only fulfilled the 1994 CDC definition. ICC patients reported significantly greater (p < 0.05) disability across all domains of the WHO DAS 2.0. Conclusions: These preliminary findings suggest that the ICC identifies a distinct subgroup found within patients complying with the 1994 CDC definition, with more severe impairment to their physical and social functioning.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent163562 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.publisherBioMed Central
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationY
dc.relation.ispartofpagefrom64-1
dc.relation.ispartofpageto64-7
dc.relation.ispartofjournalHealth and Quality of Life Outcomes
dc.relation.ispartofvolume12
dc.rights.retentionY
dc.subject.fieldofresearchClinical Sciences not elsewhere classified
dc.subject.fieldofresearchPublic Health and Health Services
dc.subject.fieldofresearchcode110399
dc.subject.fieldofresearchcode1117
dc.titleA comparison of health status in patients meeting alternative definitions for chronic fatigue syndrome/myalgic encephalomyelitis
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by/2.0
gro.facultyGriffith Health, School of Medical Science
gro.description.notepublicPage numbers are not for citation purposes. Instead, this article has the unique article number of 64.
gro.rights.copyright© 2014 Johnston et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorStaines, Don R.
gro.griffith.authorHardcastle, Sharni L.
gro.griffith.authorHuth, Teilah K.
gro.griffith.authorMarshall-Gradisnik, Sonya M.
gro.griffith.authorJohnston, Samantha
gro.griffith.authorBrenu, Ekua


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