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dc.contributor.authorAlfredson, Daviden_US
dc.contributor.authorAkhurst, R.en_US
dc.contributor.authorKorolik, Victoriaen_US
dc.contributor.editorDuncan E S Stewart Tullen_US
dc.description.abstractAim: To screen 90 clinical isolates of thermophilic Campylobacter species for putative resistance to ampicillin, erythromycin and tetracycline and perform numerical analysis to determine isolate relatedness. Methods and Results: Disc diffusion, E-test MIC and agar dilution methods were performed. Disc diffusion testing showed 87 (97%) isolates appeared resistant to ampicillin at 10 姻 14 (16%) resistant to tetracycline at 30 姻 and three (3紥) resistant to erythromycin at 15 姮 E-test MICs showed a range of 0絠to >256 mg l1 for ampicillin; 16 to >256 mg l1 for tetracycline; and >256 mg l1 for erythromycin. E-test showed 68% correlation (ᱠlog2 dilution) with agar dilution for ampicillin, 100% for erythromycin and 64% for tetracycline. Disc diffusion testing showed 100% correlation with agar dilution for erythromycin and tetracycline, and 77% for ampicillin. Numerical analyses of restriction endonuclease (RE) fragment profiles suggested a high level of isolate variation. Conclusion: The incidence of resistance of thermophilic Campylobacter spp. to erythromycin and tetracycline is low in south-east Queensland. Significance and Impact of the Study: Disc diffusion susceptibility testing may be used to screen thermophilic Campylobacter spp. for putative resistance to erythromycin and tetracycline. Agar dilution should be used to determine ampicillin susceptibility.en_US
dc.publisherBlackwell Publishing Ltden_US
dc.publisher.placeOxford, Englanden_US
dc.relation.ispartofjournalJournal of Applied Microbiologyen_US
dc.titleAntimicrobial resistance and genomic screening of clinical isolates of thermophilic Campylobacter spp. from south-east Queensland, Australiaen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Health, School of Medical Scienceen_US
gro.rights.copyrightCopyright 2003 Blackwell Publishing. The definitive version is available at []en_AU
gro.hasfulltextNo Full Text

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